Polycystic kidney disease

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Doctors who treat this condition

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Displaying 11-20 out of 22 doctors available

  1. Sayeed Khalillullah, M.D.

    Sayeed Khalillullah, M.D.

    1. Nephrologist
    1. Phoenix, AZ
    Areas of focus:

    Chronic kidney disease, End-stage renal disease, Polycystic kidney disease, Glomerular disease, Acute kidney injury

  2. Napat Leeaphorn, M.D.

    Napat Leeaphorn, M.D.

    1. Transplant Nephrologist
    1. Jacksonville, FL
    Areas of focus:

    Pre-transplant evaluation, Immunosuppressive drug therapy, Pancreas transplant, Kidney transplant, Dialysis, Continuous... renal replacement therapy, Hemodialysis, Post-transplant long-term care, Transplant rejection, Diabetic nephropathy, Kidney failure, Chronic kidney disease, End-stage renal disease, Acute kidney failure, Polycystic kidney disease

  3. Martin L. Mai, M.D.

    Martin L. Mai, M.D.

    1. Transplant Nephrologist
    1. Jacksonville, FL
    Areas of focus:

    Pre-transplant evaluation, Immunosuppressive drug therapy, Pancreas transplant, Kidney transplant, Post-transplant long...-term care, Diabetic nephropathy, Kidney failure, Chronic kidney disease, End-stage renal disease, Acute kidney failure, Polycystic kidney disease

  4. Katherine Oshel, M.D.

    Katherine Oshel, M.D.

    1. Transplant Nephrologist
    1. Jacksonville, FL
    Areas of focus:

    Pre-transplant evaluation, Immunosuppressive drug therapy, Pancreas transplant, Kidney transplant, Post-transplant long...-term care, Diabetic nephropathy, Chronic kidney disease, End-stage renal disease, Acute kidney failure, Kidney injury, Polycystic kidney disease

  5. Mary B. Prendergast, M.B., B.Ch., M.D.

    Mary B. Prendergast, M.B., B.Ch., M.D.

    1. Transplant Nephrologist
    1. Jacksonville, FL
    Areas of focus:

    Pre-transplant evaluation, Immunosuppressive drug therapy, Pancreas transplant, Kidney transplant, Post-transplant long...-term care, Diabetic nephropathy, Chronic kidney disease, End-stage renal disease, Acute kidney failure, General infectious diseases, Polycystic kidney disease, HIV/AIDS

  6. Mikel Prieto, M.D.

    Mikel Prieto, M.D.

    1. Transplant Surgeon
    1. Rochester, MN
    Areas of focus:

    Pancreas transplant, Nephrectomy, Kidney donation, Living donor kidney transplant, Donor nephrectomy, Laparoscopic kidn...ey surgery, Preemptive kidney transplant, Diabetes, Chronic kidney disease, Polycystic kidney disease, ADPKD

  7. David J. Sas, D.O.

    David J. Sas, D.O.

    1. Pediatrician
    2. Pediatric Nephrologist
    1. Rochester, MN
    Areas of focus:

    Kidney transplant, Dialysis, Continuous renal replacement therapy, Hemodialysis, Peritoneal dialysis, Nephrotic syndrom...e, Renal artery stenosis, Hydronephrosis, Shrinking kidney, Kidney stone, Renal tubular acidosis, Hyperoxaluria, Blood in urine, Urinary tract infection, Horseshoe kidney, Protein in urine, Single kidney, Kidney infection, Congenital kidney disorder, Postural proteinuria, High blood pressure in children, Childhood nephrotic syndrome, Chronic kidney disease, End-stage renal disease, Kidney injury, Polycystic kidney disease, Glomerular disease, Minimal change disease, Focal segmental glomerulosclerosis, Primary hyperoxaluria, Acute kidney injury , Renovascular disease, Kidney cyst, Multicystic kidney dysplasia, Membranoproliferative glomerulonephritis, Medullary sponge kidney, Hypercalciuria

  8. Timucin Taner, M.D., Ph.D.

    Timucin Taner, M.D., Ph.D.

    1. Transplant Surgeon
    1. Rochester, MN
    Areas of focus:

    Kidney donor evaluation, Pancreas transplant, Kidney transplant, Living donor kidney transplant, Liver transplant, Livi...ng donor liver transplant, Liver resection, Donor nephrectomy, Liver donation, Living-donor transplant, Living kidney donation, Amyloidosis, Kidney failure, Hepatopulmonary syndrome, Primary biliary cholangitis, Cirrhosis, Liver cancer, End-stage renal disease, Hepatocellular carcinoma, Cholangiocarcinoma, Alagille syndrome, Liver tumor, Polycystic kidney disease, Nonalcoholic steatohepatitis, Alcoholic hepatitis, Portal hypertension, Primary hyperoxaluria, Chronic liver disease, Alcoholic liver disease, Nonalcoholic fatty liver disease, Acute liver failure, Primary sclerosing cholangitis, Fatty liver disease, Metabolic liver disease, Polycystic liver disease, Budd-Chiari syndrome, Autoimmune hepatitis, Liver mass, Portopulmonary hypertension, Hepatorenal syndrome

  9. Vicente Torres, M.D., Ph.D.

    Vicente Torres, M.D., Ph.D.

    1. Internist
    2. Nephrologist
    1. Rochester, MN
    Areas of focus:

    Transplant, Pancreas transplant, Kidney transplant, Kidney failure, Kidney stone, Polycystic kidney disease, ADPKD, Glo...merular disease

  10. Cheryl L. Tran, M.D.

    Cheryl L. Tran, M.D.

    1. Pediatrician
    2. Pediatric Nephrologist
    1. Rochester, MN
    Areas of focus:

    Kidney transplant, Dialysis, Hemodialysis, Peritoneal dialysis, Hemolytic uremic syndrome, Nephrotic syndrome, Renal ar...tery stenosis, Hydronephrosis, Shrinking kidney, Renal tubular acidosis, Blood in urine, Urinary tract infection, Horseshoe kidney, Protein in urine, Single kidney, Kidney infection, Congenital kidney disorder, Postural proteinuria, High blood pressure in children, Childhood nephrotic syndrome, Chronic kidney disease, End-stage renal disease, Polycystic kidney disease, IgA nephropathy, Glomerular disease, Minimal change disease, Focal segmental glomerulosclerosis, Membranous nephropathy, Acute kidney injury , Renovascular disease, Kidney cyst, Multicystic kidney dysplasia, Membranoproliferative glomerulonephritis, Medullary sponge kidney

Research

Mayo Clinic is a leader in polycystic kidney disease research. Mayo Clinic researchers discovered:

  • The main gene that causes autosomal dominant polycystic kidney disease (ADPKD)
  • The gene that causes autosomal recessive polycystic kidney disease (ARPKD)
  • A gene that causes a rare form of polycystic kidney disease associated with multiple malformations (Meckel-Gruber syndrome)
  • The polycystic kidney disease proteins polycystin 1, polycystin 2 and fibrocystin
  • The polycystic kidney and liver disease gene GANAB
  • Other genes that cause kidney cyst disease, such as DNAJB11
  • A way to use CT and MRI scans to classify polycystic kidney disease and select people for clinical trials of new therapies
  • A pioneering approach to surgery to remove diseased kidneys and transplant healthy kidneys during the same surgery

Lab-based research at Mayo Clinic has focused on:

  • Explaining how mutations in the polycystic kidney disease genes lead to cyst development
  • Preclinical studies in drug therapies for polycystic kidney disease, such as octreotide and vasopressin antagonists
  • Finding effective therapies for polycystic kidney disease and liver disease
  • Improving imaging assessments of polycystic kidney and liver disease
  • Studies of polycystic kidney disease proteins in urine particles known as exosomes
  • Testing new compounds in animal models of polycystic kidney disease
  • Studies of the hairlike structures (primary cilia) implicated in polycystic kidney disease

Mayo research has shown that a new drug (tolvaptan) can dramatically slow the development and progression of polycystic kidney disease in animal models.

Mayo researchers have also shown that another drug (octreotide) delays the development of both polycystic kidney disease and polycystic liver disease and is a potential treatment option for people with liver involvement.

These medications are now in clinical trials and tolvaptan is approved for use in some countries for polycystic kidney disease. In addition, nephrologists at Mayo Clinic are working to understand how to prevent the progression of kidney (renal) disease in patients with polycystic kidney disease.

Read more about the extensive research being done at Mayo Clinic's Robert M. and Billie Kelley Pirnie Translational Polycystic Kidney Disease (PKD) Center.

The Mayo Nephrology Collaborative Group — a consortium of nephrologists located across the United States — develops and conducts studies aimed at improving treatment of patients with renal diseases, including polycystic kidney disease.

Publications

See a list of publications by Mayo Clinic doctors on polycystic kidney disease on PubMed, a service of the National Library of Medicine.

Research Profiles

By Mayo Clinic Staff

Polycystic kidney disease care at Mayo Clinic

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Diagnosis & treatmentCare at Mayo Clinic
Jan. 25, 2024
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Polycystic kidney disease

Research: It's all about patients

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Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight.