Ensayos clínicos

Inclusion Criteria: 

• Apparently healthy individuals without contra-indications for MRI scans.
• Subjects must be 18-75 years of age and able to give consent.

Exclusion Criteria:

• Individuals with contraindication to MRI scans including, but not limited to, non-MRI compatible implantable devices.
• Individuals unable to maintain a still position on the MR scanner for 80 minutes.
• Colorblind individuals (as identified using the Ishihara Color Blindness Test).
• Individuals with self-reported sensitivity to light. Individuals with hearing aids or known hearing deficiencies.
• Individuals who are currently working night shifts.
• Individuals with medical conditions or medications that potentially alter attention and alertness (e.g., hypersomnolence, obstructive sleep apnea, narcolepsy, treatment with stimulant medications (e.g., methylphenidate) or recreational drugs.
• Alcohol and caffeine use must be moderate* or less
• A score of 11 or higher on the Karolinska Sleepiness Scale (KSS), administered at the time of consent.

*The National Institute on Alcohol Abuse & Alcoholism (NIAAA) defines moderate drinking as up to four alcoholic drinks for men and three for women in any single day and a maximum of 14 drinks for men and seven drinks for women per week.