A Study of Functional MRI Response of Light on Alertness and Performance

Overview

About this study

The purpose of this study is to study the brain response to different wavelengths of light.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Apparently healthy individuals without contra-indications for MRI scans.
Subjects must be 18-75 years of age and able to give consent.

Exclusion Criteria:

Individuals with contraindication to MRI scans including, but not limited to, non-MRI compatible implantable devices.
Individuals unable to maintain a still position on the MR scanner for 80 minutes.
Colorblind individuals (as identified using the Ishihara Color Blindness Test).
Individuals with self-reported sensitivity to light. Individuals with hearing aids or known hearing deficiencies.
Individuals who are currently working night shifts.
Individuals with medical conditions or medications that potentially alter attention and alertness (e.g., hypersomnolence, obstructive sleep apnea, narcolepsy, treatment with stimulant medications (e.g., methylphenidate) or recreational drugs.
Alcohol and caffeine use must be moderate* or less
A score of 11 or higher on the Karolinska Sleepiness Scale (KSS), administered at the time of consent.

*The National Institute on Alcohol Abuse & Alcoholism (NIAAA) defines moderate drinking as up to four alcoholic drinks for men and three for women in any single day and a maximum of 14 drinks for men and seven drinks for women per week.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator David Black, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

David Black, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

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