Ensayos clínicos

Inclusion Criteria

• Presence of BE defined as ≥ 1 cm of visible columnar mucosa in the distal esophagus with intestinal metaplasia on histology.
• Absence of high grade dysplasia or EAC on baseline histology.
• BMI > 30 kg/m2 or Waist circumference > 102 cm in men, > 88 cm in women.
• Ability to give informed consent.

Exclusion Criteria

• Allergy to ω3 FFAs, fish or shellfish.
• Presence of high grade dysplasia or cancer on histology.
• Pregnant and or breastfeeding women
• Presence of esophagitis on initial endoscopy or symptoms of refractory GERD (heartburn or regurgitation ≥ 2 times a week) indicative of uncontrolled gastroesophageal reflux.
• Inability to give informed consent.
• Currently taking Omega3 FFA as prescription
• Anti-coagulant therapy (Plavix, Warfarin, Coumadin)
• AST or ALT level > three times upper limit of normal at baseline
• LDL > 200 mg/dl at baseline.
• INR > 2