Myra J. Wick, M.D., Ph.D.

Location

SUMMARY

The research of Myra J. Wick, M.D., Ph.D., includes the diagnosis and management of genetic conditions. She studies genetic diseases present before pregnancy through adulthood. In the time before birth and in the newborn intensive care unit, also called the NICU, genetic conditions are important causes of health problems and mortality.

Rapid diagnosis in the NICU may significantly impact patient management and outcomes. Hereditary cancer syndromes are usually identified in adulthood. The diagnosis of a cancer that's genetically passed down from a family member has significant implications for clinical management and long-term health outcomes.

Focus areas

• Investigate and improve the use of noninvasive technology to screen for genetic diseases. This screening is in early pregnancy and in twin pregnancies.
• Examine the use and outcome of rapid whole-genome sequencing, also called WGS, in the setting of the NICU. This test gives fast genetic information, allowing the NICU team and the family to make health care decisions for the newborn.
• Research the use of rapid whole-genome sequencing in the prenatal setting, which is prior to birth. This test provides rapid genetic information when there is concern that a baby may have signs of a genetic condition before delivery.
• Research-based banking of umbilical cord blood, collected after delivery, for future research testing.
• Update screening and surveillance guidelines for individuals with hereditary cancer syndromes.
• Study and carry out new clinical workflows to improve care for patients and families with hereditary cancer syndromes.

Significance to patient care

Dr. Wick's research works to directly improve the diagnosis and management of genetic conditions from before pregnancy through adulthood.

Professional highlights

• Board member, American Board of Medical Genetics and Genomics, 2022-present.
• Committee member, Genetic/Familial High Risk Assessment: Breast, Ovarian and Pancreatic, National Comprehensive Cancer Network, 2014-present.
• Medical editor, Mayo Clinic Guide to a Healthy Pregnancy, Mayo Clinic.
  • 2018.
  • 2017.
  • 2010.