Unraveling the genetic basis for disease
Backed by a team approach and a rich database of tissue samples and patient data, the Department of Clinical Genomics-Research is at the forefront of genomics-based research on everything from common forms of cancer to rare inherited disorders.
Overview
The Department of Clinical Genomics-Research at Mayo Clinic conducts research on a wide range of diseases and conditions that have a genetic basis, including common forms of cancer such as breast cancer, and rare and novel genetic disorders, such as lysosomal storage diseases.
The overarching goal of research within the Department of Clinical Genomics-Research is to further the scientific understanding of genetic-based diseases in order to help improve prevention, diagnosis and treatment for each patient.
Clinical genomics is truly a cross-specialty study. Genomics researchers work closely with their counterparts in many other research and clinical areas at Mayo Clinic, including the Department of Clinical Genomics, which includes experienced board-certified medical geneticists and certified genetic counselors who tailor care to each patient's needs.
Research being conducted in the Department of Clinical Genomics-Research also provides opportunities to participate in genetic research studies to improve overall patient care.
Research by our investigators — who are experts in medical genetics, neurology, pediatrics and other specialties — may eventually lead to better methods of screening, prevention and treatment for a wide array of genetic disorders. Our researchers are investigating breast cancer, ovarian cancer, colon cancer, congenital disorders of glycosylation, melanoma, lysosomal storage disease, neurofibromatosis, and rare or suspected genetic disorders.
The research chair for the Department of Clinical Genomics-Research is physician-scientist David R. Deyle, M.D., a medical geneticist at Mayo Clinic in Rochester, Minnesota, and an assistant professor of medical genetics at Mayo Clinic College of Medicine and Science. Dr. Deyle conducts research on improved methods of targeted genomic editing using viral vectors for the precise alteration of the human genome.