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Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume

Overview

About this study

The purpose of this study is to evaluate whether PBV derived from contrast echocardiography can serve as a non-invasive surrogate for invasive pulmonary artery wedge pressure (PAWP) during exercise. Also, to compare changes in PBV with exercise in patients with and without heart failure and pulmonary vascular disease.

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients referred to the cardiac catheterization laboratory for invasive exercise right heart catheterization for evaluating exertional dyspnea. We will include patients with normal or low EF, and across the spectrum of pulmonary hypertension severity.

Exclusion Criteria: 

  • Patient inability or unwillingness to undergo echocardiography including a contrast method, or if echocardiography would, in the opinion of the investigator, somehow compromise the quality of data acquisition for the clinical case.
  • Prior adverse reaction to echo contrast administration.

Note: Other protocol defined Inclusion/Exclusion criteria may apply.

Eligibility last updated 9/13/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Barry Borlaug, M.D.

Contact us for the latest status

Contact information:

RST Borlaug Study Team

(507) 255-2200

More information

Publications

Publications are currently not available

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CLS-20566565

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