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Adipose Tissue Blood Flow of Older Adults

Overview

About this study

The purpose of this study is to determine the differences in basal and glucse responsiveness blood flow in upperbody subuctaneous adipose tissue of older adults will be compared to younger adults. Blood flow measures will be couple with adipose tissue biopsies to understand alterations in intraceulluar tissue pathways that might regulate blood flow. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Non-obese (BMI 20-25.0 kg/m^2) adults.
  • 10 young (18-35y) and 10 older (65-80y) with both age groups balanced for sex (5F and 5M each).
  • All subjects will not have cardiometabolic diseases (e.g., T2DM, HTN) and will not be taking anticoagulants, nor prescriptions or supplements that effect adipose tissue metabolism (i.e., statins, Thiazolidinediones, niacin, atypical antipsychotics, or fish oil).

Exclusion Criteria:

  • < 18 years of age.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 5/15/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Kelli Lytle, Ph.D.

Open for enrollment

Contact information:

Kelli Lytle Ph.D.

(507) 255-1488

Lytle.Kelli@mayo.edu

More information

Publications

Publications are currently not available

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CLS-20558965

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