A Study to Evaluate the Risk of Adverse Renal Events When a Renal Transplant Recipient Becomes Pregnant

Overview

About this study

The purpose of this study is to test the hypothesis that pregnancy post-transplant will increase the risk of adverse renal events (defined as acute rejection, reduction in GFR by 30%, new or worsening proteinuria, or graft-loss). The risk will be increased in women with complications in pregnancy, such as preeclampsia or pre-term delivery.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

All women transplanted at Mayo Clinic (all 3 sites).
Ages 18-44 at time of transplant.
Transplant from 1/1/1996 to 12/31/2014, with grafts that functioned for 2 years. This will include recipients of dual organ transplantation.

Exclusion Criteria:

Graft functioning for less than 2 years after transplant.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Andrea Kattah, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Andrea Kattah, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials