Recovery of Left Ventricular Systolic Function and Atrial Fibrillation Recurrence after Restoration of Sinus Rhythm in Patients with Atrial Fibrillation

Overview

About this study

The objectives of this study are: (1) to analyze beat-to-beat variability and the variations of R-R interval to pre-preceding R-R interval (RRp/RRpp) ratio of left ventricular (LV) function by strain imaging (2D speckle tracking echocardiography) in patients with atrial fibrillation (AF) undergoing electrical cardioversion(ECV) or radiofrequency catheter ablation (RFCA) as a predictor of a recovery of LV function and volume after restoration of sinus rhythm , (2) to evaluate left atrial mechanics as a predictor of for AF recurrence after electrical cardioversion (ECV) or radiofrequency catheter ablation (RFCA)

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Age more than 18 years
Non-valvular atrial fibrillation
AF of <12 months duration

Exclusion Criteria:

Mitral stenosis
Congenital heart disease
Cardiomyopathy (Infiltrative, hypertrophic, dilated or ischemic)
History of prior cardiac surgery
History of aortic or mitral valve prosthesis
Paced Rhythm
Thyrotoxicosis
History of moderate or greater mitral regurgitation or stenosis
Prior radiofrequency ablation or surgical maze procedure.
< 18 years of age
Inability to give consent.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Rowlens Melduni, M.D., M.P.H.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Rowlens Melduni, M.D., M.P.H.

Closed for enrollment

More information

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