Publications

1. Singh NA, Alnobani A, Graff-Radford J, Machulda MM, Mielke MM, Schwarz CG, Senjem ML, Jack CR Jr, Lowe VJ, Kanekiyo T, Josephs KA, Whitwell JL. Relationships between PET and blood plasma biomarkers in corticobasal syndrome. Alzheimers Dement. 2024 Jun 17 Epub 2024 June 17
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2. Meade G, Machulda MM, Clark HM, Duffy JR, Botha H, Whitwell JL, Josephs KA, Utianski RL. Identifying and Addressing Functional Communication Challenges in Patients With Behavioral Variant Frontotemporal Dementia. Am J Speech Lang Pathol. 2024 Jun 6; 1-17 Epub 2024 June 06
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3. Garcia-Guaqueta DP, Stephens YC, Ali F, Utianski RL, Duffy JR, Clark HM, Thu Pham NT, Machulda MM, Lowe VJ, Dickson DW, Whitwell JL, Josephs KA. Comparing classic-onset corticobasal syndrome to speech/language-onset corticobasal syndrome. Parkinsonism Relat Disord. 2024 Jun 3; 125:107025 Epub 2024 June 03
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4. Kouri N, Frankenhauser I, Peng Z, Labuzan SA, Boon BDC, Moloney CM, Pottier C, Wickland DP, Caetano-Anolles K, Corriveau-Lecavalier N, Tranovich JF, Wood AC, Hinkle KM, Lincoln SJ, Spychalla AJ, Senjem ML, Przybelski SA, Engelberg-Cook E, Schwarz CG, Kwan RS, Lesser ER, Crook JE, Carter RE, Ross OA, Lachner C, Ertekin-Taner N, Ferman TJ, Fields JA, Machulda MM, Ramanan VK, Nguyen AT, Reichard RR, Jones DT, Graff-Radford J, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K, Day GS, Duara R, Graff-Radford NR, Dickson DW, Lowe VJ, Vemuri P, Murray ME. Clinicopathologic Heterogeneity and Glial Activation Patterns in Alzheimer Disease. JAMA Neurol. 2024 Jun 1; 81 (6):619-629
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5. Singh NA, Graff-Radford J, Machulda MM, Carlos AF, Schwarz CG, Senjem ML, Jack CR Jr, Lowe VJ, Josephs KA, Whitwell JL. Atypical Alzheimer's disease: new insights into an overlapping spectrum between the language and visual variants. J Neurol. 2024 Jun; 271 (6):3571-3585 Epub 2024 Mar 29
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6. Gatto RG, Pham NTT, Duffy JR, Clark HM, Utianski RL, Botha H, Machulda MM, Lowe VJ, Schwarz CG, Jack CR Jr, Josephs KA, Whitwell JL. Multimodal cross-examination of progressive apraxia of speech by diffusion tensor imaging-based tractography and Tau-PET scans. Hum Brain Mapp. 2024 Jun 1; 45 (8):e26704
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7. Tetzloff KA, Martin PR, Duffy JR, Utianski RL, Clark HM, Botha H, Machulda MM, Thu Pham NT, Schwarz CG, Senjem ML, Jack CR Jr, Lowe VJ, Josephs KA, Whitwell JL. Longitudinal flortaucipir, metabolism and volume differ between phonetic and prosodic speech apraxia. Brain. 2024 May 3; 147 (5):1696-1709
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8. Karstens AJ, Christianson TJ, Lundt ES, Machulda MM, Mielke MM, Fields JA, Kremers WK, Graff-Radford J, Vemuri P, Jack CR Jr, Knopman DS, Petersen RC, Stricker NH. Mayo normative studies: regression-based normative data for ages 30-91 years with a focus on the Boston Naming Test, Trail Making Test and Category Fluency. J Int Neuropsychol Soc. 2024 May; 30 (4):389-401 Epub 2023 Nov 28
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9. Sintini I, Singh NA, Li D, Mielke MM, Machulda MM, Schwarz CG, Senjem ML, Jack CR Jr, Lowe VJ, Graff-Radford J, Josephs KA, Whitwell JL. Plasma glial fibrillary acidic protein in the visual and language variants of Alzheimer's disease. Alzheimers Dement. 2024 May; 20 (5):3679-3686 Epub 2024 Mar 25
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10. Black JA, Pham NTT, Ali F, Machulda MM, Lowe VJ, Josephs KA, Whitwell JL. Frontal hypometabolism in the diagnosis of progressive supranuclear palsy clinical variants. J Neurol. 2024 Apr 17 [Epub ahead of print]
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11. Singh NA, Goodrich AW, Graff-Radford J, Machulda MM, Sintini I, Carlos AF, Robinson CG, Reid RI, Lowe VJ, Jack CR Jr, Petersen RC, Boeve BF, Josephs KA, Kantarci K, Whitwell JL. Altered structural and functional connectivity in Posterior Cortical Atrophy and Dementia with Lewy bodies. Neuroimage. 2024 Apr 15; 290:120564 Epub 2024 Mar 03
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12. Garcia-Guaqueta DP, Botha H, Utianski RL, Duffy JR, Clark HM, Goodrich AW, Pham NTT, Machulda MM, Baker M, Rademakers R, Whitwell JL, Josephs KA. Progression to corticobasal syndrome: a longitudinal study of patients with nonfluent primary progressive aphasia and primary progressive apraxia of speech. J Neurol. 2024 Apr 7 Epub 2024 Apr 07
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13. Corriveau-Lecavalier N, Barnard LR, Botha H, Graff-Radford J, Ramanan VK, Lee J, Dicks E, Rademakers R, Boeve BF, Machulda MM, Fields JA, Dickson DW, Graff-Radford N, Knopman DS, Lowe VJ, Petersen RC, Jack CR Jr, Jones DT. Uncovering the distinct macro-scale anatomy of dysexecutive and behavioural degenerative diseases. Brain. 2024 Apr 4; 147 (4):1483-1496
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14. Meade G, Whitwell JL, Dickson DW, Duffy JR, Clark HM, Ahlskog JE, Machulda MM, Josephs KA, Utianski RL. Primary Progressive Apraxia of Speech Caused by TDP-43: A Case Report. Neurol Genet. 2024 Apr; 10 (2):e200134 Epub 2024 Mar 19
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15. Robinson CG, Goodrich AW, Weigand SD, Pham NTT, Carlos AF, Buciuc M, Murray ME, Nguyen AT, Reichard RR, Knopman DS, Petersen RC, Dickson DW, Utianski RL, Whitwell JL, Josephs KA, Machulda MM. Determinants of confrontation naming deficits on the Boston Naming Test associated with transactive response DNA-binding protein 43 pathology. J Int Neuropsychol Soc. 2024 Mar 25; 1-9 [Epub ahead of print]
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16. Shir D, Corriveau-Lecavalier N, Bermudez Noguera C, Barnard L, Pham NTT, Botha H, Duffy JR, Clark HM, Utianski RL, Knopman DS, Petersen RC, Boeve BF, Murray ME, Nguyen AT, Reichard RR, Dickson DW, Day GS, Kremers WK, Graff-Radford NR, Jones DT, Machulda MM, Fields JA, Whitwell JL, Josephs KA, Graff-Radford J. Clinicoradiological and neuropathological evaluation of primary progressive aphasia. J Neurol Neurosurg Psychiatry. 2024 Mar 21 [Epub ahead of print]
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17. Robinson CG, Lee J, Min PH, Przybelski SA, Josephs KA, Jones DT, Graff-Radford J, Boeve BF, Knopman DS, Jack CR Jr, Petersen RC, Machulda MM, Fields JA, Lowe VJ. Significance of a positive tau PET scan with a negative amyloid PET scan. Alzheimers Dement. 2024 Mar; 20 (3):1923-1932 Epub 2023 Dec 30
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18. Jack CR Jr, Wiste HJ, Algeciras-Schimnich A, Weigand SD, Figdore DJ, Lowe VJ, Vemuri P, Graff-Radford J, Ramanan VK, Knopman DS, Mielke MM, Machulda MM, Fields J, Schwarz CG, Cogswell PM, Senjem ML, Therneau TM, Petersen RC. Comparison of plasma biomarkers and amyloid PET for predicting memory decline in cognitively unimpaired individuals. Alzheimers Dement. 2024 Mar; 20 (3):2143-2154 Epub 2024 Jan 24
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19. Badihian N, Ali F, Botha H, Savica R, Machulda MM, Clark HM, Stierwalt JAG, Pham NTT, Baker MC, Rademakers R, Lowe V, Whitwell JL, Josephs KA. The MAPT p.E342K and p.R406W mutations are associated with progressive supranuclear palsy with atypical features. Parkinsonism Relat Disord. 2024 Feb; 119:105962 Epub 2023 Dec 17
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20. Gatto RG, Martin PR, Utianski RL, Duffy JR, Clark HM, Botha H, Machulda MM, Josephs KA, Whitwell JL. Diffusion tensor imaging-based multi-fiber tracking reconstructions can regionally differentiate phonetic versus prosodic subtypes of progressive apraxia of speech. Cortex. 2024 Feb; 171:272-286 Epub 2023 Nov 08
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21. Raghavan S, Przybelski SA, Lesnick TG, Fought AJ, Reid RI, Gebre RK, Windham BG, Algeciras-Schimnich A, Machulda MM, Vassilaki M, Knopman DS, Jack CR Jr, Petersen RC, Graff-Radford J, Vemuri P. Vascular risk, gait, behavioral, and plasma indicators of VCID. Alzheimers Dement. 2024 Feb; 20 (2):1201-1213 Epub 2023 Nov 06
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22. Stricker NH, Stricker JL, Frank RD, Fan WZ, Christianson TJ, Patel JS, Karstens AJ, Kremers WK, Machulda MM, Fields JA, Graff-Radford J, Jack CR Jr, Knopman DS, Mielke MM, Petersen RC. Stricker Learning Span criterion validity: a remote self-administered multi-device compatible digital word list memory measure shows similar ability to differentiate amyloid and tau PET-defined biomarker groups as in-person Auditory Verbal Learning Test. J Int Neuropsychol Soc. 2024 Feb; 30 (2):138-151 Epub 2023 June 30
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23. Shir D, Corriveau-Lecavalier N, Graff-Radford J, Machulda MM, Knopman DS, Petersen RC, Nguyen AT, Dickson DW, Jones DT. Case report: pre-symptomatic clinical and metabolic profile in posterior cortical atrophy and dementia with Lewy bodies. Neurocase. 2024 Feb; 30 (1):1-7 Epub 2024 May 17
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24. Corriveau-Lecavalier N, Barnard LR, Przybelski SA, Gogineni V, Botha H, Graff-Radford J, Ramanan VK, Forsberg LK, Fields JA, Machulda MM, Rademakers R, Gavrilova RH, Lapid MI, Boeve BF, Knopman DS, Lowe VJ, Petersen RC, Jack CR, Kantarci K, Jones DT. Assessing network degeneration and phenotypic heterogeneity in genetic frontotemporal lobar degeneration by decoding FDG-PET. Neuroimage Clin. 2024; 41:103559 Epub 2023 Dec 22
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25. Robinson CG, Coleman T, Buciuc M, Singh NA, Pham NTT, Machulda MM, Graff-Radford J, Whitwell JL, Josephs KA. Behavioral and Neuropsychiatric Differences Across Two Atypical Alzheimer's Disease Variants: Logopenic Progressive Aphasia and Posterior Cortical Atrophy. J Alzheimers Dis. 2024; 97(2):895-908.
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26. Sintini I, Corriveau-Lecavalier N, Jones DT, Machulda MM, Gunter JL, Schwarz CG, Botha H, Carlos AF, Kamykowski MG, Singh NA, Petersen RC, Jack CR Jr, Lowe VJ, Graff-Radford J, Josephs KA, Whitwell JL. Longitudinal default mode sub-networks in the language and visual variants of Alzheimer's disease. Brain Commun. 2024; 6 (2):fcae005 Epub 2024 Jan 08
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27. Krell-Roesch J, Syrjanen JA, Bezold J, Trautwein S, Barisch-Fritz B, Boes K, Woll A, Forzani E, Kremers WK, MacHulda MM, Mielke MM, Knopman DS, Petersen RC, Vassilaki M, Geda YE. Physical activity and trajectory of cognitive change in older persons: Mayo Clinic study of aging. Advances in Alzheimer's Disease. 2024; 10:3-14
    
28. Gatto RG, Meade G, Duffy JR, Clark HM, Utianski RL, Botha H, Machulda MM, Josephs KA, Whitwell JL. Combined assessment of progressive apraxia of speech brain microstructure by diffusion tensor imaging tractography and multishell neurite orientation dispersion and density imaging. Brain Behav. 2024 Jan; 14 (1):e3346
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29. Orlandi F, Carlos AF, Ali F, Clark HM, Duffy JR, Utianski RL, Botha H, Machulda MM, Stephens YC, Schwarz CG, Senjem ML, Jack CR, Agosta F, Filippi M, Dickson DW, Josephs KA, Whitwell JL. Histologic tau lesions and magnetic resonance imaging biomarkers differ across two progressive supranuclear palsy variants. Brain Commun. 2024; 6 (2):fcae113 Epub 2024 Apr 05
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30. Carlos AF, Weigand SD, Duffy JR, Clark HM, Utianski RL, Machulda MM, Botha H, Thu Pham NT, Lowe VJ, Schwarz CG, Whitwell JL, Josephs KA. Volumetric analysis of hippocampal subregions and subfields in left and right semantic dementia. Brain Commun. 2024; 6 (2):fcae097 Epub 2024 Mar 25
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31. Youssef H, Gatto RG, Pham NTT, Petersen RC, Machulda MM, Reichard RR, Dickson DW, Jack CR, Whitwell JL, Josephs KA. TDP-43 Is Associated with Subiculum and Cornu Ammonis 1 Hippocampal Subfield Atrophy in Primary Age-Related Tauopathy. J Alzheimers Dis. 2024; 99 (3):1023-1032
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32. Carlos AF, Sekiya H, Koga S, Gatto RG, Casey MC, Pham NTT, Sintini I, Machulda MM, Jack CR, Lowe VJ, Whitwell JL, Petrucelli L, Reichard RR, Petersen RC, Dickson DW, Josephs KA. Clinicopathologic features of a novel star-shaped transactive response DNA-binding protein 43 (TDP-43) pathology in the oldest old. J Neuropathol Exp Neurol. 2023 Dec 22; 83 (1):36-52
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33. Sintini I, Graff-Radford J, Schwarz CG, Machulda MM, Singh NA, Carlos AF, Senjem ML, Jr CRJ, Lowe VJ, Josephs KA, Whitwell JL. Longitudinal rates of atrophy and tau accumulation differ between the visual and language variants of atypical Alzheimer's disease. Alzheimers Dement. 2023 Oct; 19 (10):4396-4406 Epub 2023 July 23
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34. Marinelli JP, Reed NS, Lohse CM, Fussell WL, Petersen RC, Machulda MM, Vassilaki M, Carlson ML. Cognitive Performance, Sociodemographic Factors, Pure-Tone Audiometry, and their Association with Speech Discrimination: A Prospective Population-Based Study of 1,061 Older Adults. Otol Neurotol. 2023 Oct 1; 44 (9):860-865 Epub 2023 Aug 23
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35. Utianski RL, Meade G, Duffy JR, Clark HM, Botha H, Machulda MM, Dickson DW, Whitwell JL, Josephs KA. Longitudinal characterization of patients with progressive apraxia of speech without clearly predominant phonetic or prosodic speech features. Brain Lang. 2023 Oct; 245:105314 Epub 2023 Aug 20
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36. Singh NA, Martin PR, Graff-Radford J, Machulda MM, Carrasquillo MM, Ertekin-Taner N, Josephs KA, Whitwell JL. APOE epsilon4 influences within and between network functional connectivity in posterior cortical atrophy and logopenic progressive aphasia. Alzheimers Dement. 2023 Sep; 19 (9):3858-3866 Epub 2023 Mar 31
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37. Stricker NH, Twohy EL, Albertson SM, Karstens AJ, Kremers WK, Machulda MM, Fields JA, Jack CR Jr, Knopman DS, Mielke MM, Petersen RC. Mayo-PACC: A parsimonious preclinical Alzheimer's disease cognitive composite comprised of public-domain measures to facilitate clinical translation. Alzheimers Dement. 2023 Jun; 19 (6):2575-2584 Epub 2022 Dec 24
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38. Corriveau-Lecavalier N, Barnard LR, Lee J, Dicks E, Botha H, Graff-Radford J, Machulda MM, Boeve BF, Knopman DS, Lowe VJ, Petersen RC, Jack CR Jr, Jones DT. Deciphering the clinico-radiological heterogeneity of dysexecutive Alzheimer's disease. Cereb Cortex. 2023 May 24; 33 (11):7026-7043
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39. Chandregowda A, Clark HM, Machulda MM, Pham NTT, Lowe VJ, Josephs KA, Whitwell JL. A Case of Atypical Alzheimer's Disease With Clinical Manifestation That Straddled the Boundary Between Primary Progressive Aphasia and Posterior Cortical Atrophy. Neurologist. 2023 May 1; 28 (3):195-197 Epub 2023 May 01
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40. Robinson CG, Duffy JR, Clark HA, Utianski RL, Machulda MM, Botha H, Singh NA, Pham NTT, Ertekin-Taner N, Dickson DW, Lowe VJ, Whitwell JL, Josephs KA. Clinicopathological associations of hemispheric dominance in primary progressive apraxia of speech. Eur J Neurol. 2023 May; 30 (5):1209-1219 Epub 2023 Mar 15
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41. Pavone C, Weigand SW, Ali F, Clark HM, Botha H, Machulda MM, Savica R, Pham NTT, Grijalva RM, Schwarz CG, Senjem ML, Agosta F, Filippi M, Jack CR, Lowe VJ, Josephs KA, Whitwell JL. Longitudinal clinical decline and baseline predictors in progressive supranuclear palsy. Parkinsonism Relat Disord. 2023 Feb; 107:105290 Epub 2023 Jan 16
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42. Vassilaki M, Syrjanen JA, Krell-Roesch J, Graff-Radford J, Vemuri P, Scharf EL, Machulda MM, Fields JA, Kremers WK, Lowe VJ, Jack CR Jr, Knopman DS, Petersen RC, Geda YE. Association of Cerebrovascular Imaging Biomarkers, Depression, and Anxiety, with Mild Cognitive Impairment. J Alzheimers Dis Rep. 2023; 7 (1):1237-1246 Epub 2023 Nov 03
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43. Tetzloff KA, Duffy JR, Clark HM, Pham NTT, Machulda MM, Botha H, Jack CR, Dickson DW, Lowe VJ, Josephs KA, Whitwell JL, Utianski RL. Amyloid and Tau PET Positivity in Progressive Agrammatic Aphasia and Apraxia of Speech. J Alzheimers Dis. 2023; 96 (4):1759-1765
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44. Beba A, Peterson SM, Brennan PC, O'Byrne J, Machulda MM, Jannetto PJ, Vemuri P, Lewallen DG, Maradit Kremers H, Vassilaki M. Correlation of Blood Metal Concentrations with Cognitive Scores and Neuroimaging Findings in Patients with Total Joint Arthroplasty. J Alzheimers Dis. 2023; 94 (4):1335-1342
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45. Satoh R, Arani A, Senjem ML, Duffy JR, Clark HM, Utianski RL, Botha H, Machulda MM, Jack CR Jr, Whitwell JL, Josephs KA. Spatial patterns of elevated magnetic susceptibility in progressive apraxia of speech. Neuroimage Clin. 2023; 38:103394 Epub 2023 Mar 28
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46. Carlos AF, Machulda MM, Rutledge MH, Nguyen AT, Reichard RR, Baker MC, Rademakers R, Dickson DW, Petersen RC, Josephs KA. Comparison of Clinical, Genetic, and Pathologic Features of Limbic and Diffuse Transactive Response DNA-Binding Protein 43 Pathology in Alzheimer's Disease Neuropathologic Spectrum. J Alzheimers Dis. 2023; 93 (4):1521-1535
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47. Singh NA, Martin PR, Graff-Radford J, Sintini I, Machulda MM, Duffy JR, Gunter JL, Botha H, Jones DT, Lowe VJ, Jack CR Jr, Josephs KA, Whitwell JL. Altered within- and between-network functional connectivity in atypical Alzheimer's disease. Brain Commun. 2023; 5 (4):fcad184 Epub 2023 June 14
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48. Singh NA, Graff-Radford J, Machulda MM, Pham NTT, Schwarz CG, Reid RI, Lowe VJ, Petersen RC, Jack CR, Josephs KA, Whitwell JL. Diffusivity Changes in Posterior Cortical Atrophy and Logopenic Progressive Aphasia: A Longitudinal Diffusion Tensor Imaging Study. J Alzheimers Dis. 2023; 94 (2):709-725
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49. Singh NA, Graff-Radford J, Machulda MM, Schwarz CG, Baker MC, Rademakers R, Ertekin-Taner N, Lowe VJ, Josephs KA, Whitwell JL. Atypical Alzheimer's disease phenotypes with normal or borderline PET biomarker profiles. J Neurol. 2022 Dec; 269(12):6613-6626. Epub 2022 Aug 24.
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50. Marinelli JP, Lohse CM, Fussell WL, Petersen RC, Reed NS, Machulda MM, Vassilaki M, Carlson ML. Association between hearing loss and development of dementia using formal behavioural audiometric testing within the Mayo Clinic Study of Aging (MCSA): a prospective population-based study. Lancet Healthy Longev. 2022 Dec; 3 (12):e817-e824 Epub 2022 Nov 18
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51. Sintini I, Duffy JR, Clark HM, Utianski RL, Botha H, Machulda MM, Senjem ML, Strand EA, Schwarz CG, Lowe VJ, Jack CR, Josephs KA, Whitwell JL. Functional connectivity to the premotor cortex maps onto longitudinal brain neurodegeneration in progressive apraxia of speech. Neurobiol Aging. 2022 Dec; 120:105-116 Epub 2022 Sept 02
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52. Josephs KA, Tosakulwong N, Gatto RG, Weigand SD, Ali F, Botha H, Graff-Radford J, Machulda MM, Savica R, Schwarz CG, Senjem ML, Boeve BF, Kantarci K, Jones DT, Ramanan VK, Fields JA, Reichard RR, Dickson DW, Petersen RC, Jack CR Jr, Lowe VJ, Whitwell JL. Optimum Differentiation of Frontotemporal Lobar Degeneration from Alzheimer Disease Achieved with Cross-Sectional Tau Positron Emission Tomography. Ann Neurol. 2022 Dec; 92 (6):1016-1029 Epub 2022 Aug 29
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53. Pham NTT, Graff-Radford J, Machulda MM, Spychalla AJ, Schwarz CG, Senjem ML, Lowe VJ, Vemuri P, Kantarci K, Knopman DS, Petersen RC, Jack CR, Josephs KA, Whitwell JL. Regional white matter hyperintensities in posterior cortical atrophy and logopenic progressive aphasia. Neurobiol Aging. 2022 Nov; 119:46-55 Epub 2022 July 28
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54. Vassilaki M, Kremers WK, Machulda MM, Knopman DS, Petersen RC, Laporta ML, Berry DJ, Lewallen DG, Maradit Kremers H. Long-term Cognitive Trajectory After Total Joint Arthroplasty. JAMA Netw Open. 2022 Nov 01; 5(11):e2241807.
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55. Chandregowda A, Duffy JR, Machulda MM, Lowe VJ, Whitwell JL, Josephs KA. Dynamic aphasia with emerging agrammatism, anomia, and aberrant frontal behaviors in a case of atypical parkinsonism. Neurol Clin Neurosci. 2022 Sep; 10 (5):262-265 Epub 2022 July 20
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56. Corriveau-Lecavalier N, Alden EC, Stricker NH, Machulda MM, Jones DT. Failed Performance on the Test of Memory Malingering and Misdiagnosis in Individuals with Early-Onset Dysexecutive Alzheimer's Disease. Arch Clin Neuropsychol. 2022 Aug 23; 37 (6):1199-1207
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57. Corriveau-Lecavalier N, Machulda MM, Botha H, Graff-Radford J, Knopman DS, Lowe VJ, Fields JA, Stricker NH, Boeve BF, Jack CR Jr, Petersen RC, Jones DT. Phenotypic subtypes of progressive dysexecutive syndrome due to Alzheimer's disease: a series of clinical cases. J Neurol. 2022 Aug; 269 (8):4110-4128 Epub 2022 Feb 25
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58. Shir D, Graff-Radford J, Machulda MM, Pham NTT, Jack CR Jr, Lowe VJ, Whitwell JL, Josephs KA. Posterior cortical atrophy: Primary occipital variant. Eur J Neurol. 2022 Jul; 29 (7):2138-2143 Epub 2022 Mar 30
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59. Whitwell JL, Martin PR, Graff-Radford J, Machulda MM, Sintini I, Buciuc M, Senjem ML, Schwarz CG, Botha H, Carrasquillo MM, Ertekin-Taner N, Lowe VJ, Jack CR, Josephs KA. Investigating Heterogeneity and Neuroanatomic Correlates of Longitudinal Clinical Decline in Atypical Alzheimer Disease. Neurology. 2022 Jun 13; 98 (24):e2436-e2445 Epub 2022 June 13
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60. Singh NA, Tosakulwong N, Graff-Radford J, Machulda MM, Pham NTT, Sintini I, Weigand SD, Schwarz CG, Senjem ML, Carrasquillo MM, Ertekin-Taner N, Jack CR Jr, Lowe VJ, Josephs KA, Whitwell JL. APOE epsilon4 influences medial temporal atrophy and tau deposition in atypical Alzheimer's disease. Alzheimers Dement. 2022 Jun 12 Epub 2022 June 12
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61. Vassilaki M, Aakre JA, Castillo A, Chamberlain AM, Wilson PM, Kremers WK, Mielke MM, Geda YE, Machulda MM, Alhurani RE, Graff-Radford J, Vemuri P, Lowe VJ, Jack CR Jr, Knopman DS, Petersen RC. Association of neighborhood socioeconomic disadvantage and cognitive impairment. Alzheimers Dement. 2022 Jun 6 Epub 2022 June 06
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62. Syrjanen JA, Campbell MR, Algeciras-Schimnich A, Vemuri P, Graff-Radford J, Machulda MM, Bu G, Knopman DS, Jack CR Jr, Petersen RC, Mielke MM. Associations of amyloid and neurodegeneration plasma biomarkers with comorbidities. Alzheimers Dement. 2022 Jun; 18(6):1128-1140. Epub 2021 Sep 27.
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63. Saboo KV, Hu C, Varatharajah Y, Przybelski SA, Reid RI, Schwarz CG, Graff-Radford J, Knopman DS, Machulda MM, Mielke MM, Petersen RC, Arnold PM, Worrell GA, Jones DT, Jack CR Jr, Iyer RK, Vemuri P. Deep learning identifies brain structures that predict cognition and explain heterogeneity in cognitive aging. Neuroimage. 2022 May 1; 251:119020 Epub 2022 Feb 20
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64. Ramanan VK, Heckman MG, Lesnick TG, Przybelski SA, Cahn EJ, Kosel ML, Murray ME, Mielke MM, Botha H, Graff-Radford J, Jones DT, Lowe VJ, Machulda MM, Jack CR Jr, Knopman DS, Petersen RC, Ross OA, Vemuri P. Tau polygenic risk scoring: a cost-effective aid for prognostic counseling in Alzheimer's disease. Acta Neuropathol. 2022 May; 143 (5):571-583 Epub 2022 Apr 12
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65. Polsinelli AJ, Machulda MM, Martin PR, Duffy JR, Clark HM, Butts AM, Botha H, Lowe VJ, Whitwell JL, Josephs KA, Utianski RL. Neuropsychological Profiles of Patients with Progressive Apraxia of Speech and Aphasia. J Int Neuropsychol Soc. 2022 May; 28 (5):441-451 Epub 2021 July 22
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66. Weil EL, Noseworthy PA, Lopez CL, Rabinstein AA, Friedman PA, Attia ZI, Yao X, Siontis KC, Kremers WK, Christopoulos G, Mielke MM, Vemuri P, Jack CR Jr, Gersh BJ, Machulda MM, Knopman DS, Petersen RC, Graff-Radford J. Artificial Intelligence-Enabled Electrocardiogram for Atrial Fibrillation Identifies Cognitive Decline Risk and Cerebral Infarcts. Mayo Clin Proc. 2022 May; 97 (5):871-880
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67. Grijalva RM, Pham NTT, Huang Q, Martin PR, Ali F, Clark HM, Duffy JR, Utianski RL, Botha H, Machulda MM, Weigand SD, Ahlskog JE, Dickson DW, Josephs KA, Whitwell JL. Brainstem Biomarkers of Clinical Variant and Pathology in Progressive Supranuclear Palsy. Mov Disord. 2022 Apr; 37 (4):702-712 Epub 2021 Dec 31
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68. Mielke MM, Aakre JA, Algeciras-Schimnich A, Proctor NK, Machulda MM, Eichenlaub U, Knopman DS, Vemuri P, Graff-Radford J, Jack CR Jr, Petersen RC, Dage JL. Comparison of CSF phosphorylated tau 181 and 217 for cognitive decline. Alzheimers Dement. 2022 Apr; 18 (4):602-611 Epub 2021 July 26
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69. Kara F, Joers JM, Deelchand DK, Park YW, Przybelski SA, Lesnick TG, Senjem ML, Zeydan B, Knopman DS, Lowe VJ, Vemuri P, Mielke MM, Machulda MM, Jack CR, Petersen RC, Oz G, Kantarci K. (1)H MR spectroscopy biomarkers of neuronal and synaptic function are associated with tau deposition in cognitively unimpaired older adults. Neurobiol Aging. 2022 Apr; 112:16-26 Epub 2022 Jan 05
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70. Vassilaki M, Aakre JA, Kremers WK, Mielke MM, Geda YE, Machulda MM, Knopman DS, Vemuri P, Lowe VJ, Jack CR Jr, Roberson ED, Gerstenecker A, Martin RC, Kennedy RE, Marson DC, Petersen RC. Association of Performance on the Financial Capacity Instrument-Short Form With Brain Amyloid Load and Cortical Thickness in Older Adults. Neurol Clin Pract. 2022 Apr; 12 (2):113-124
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71. Huo N, Vemuri P, Graff-Radford J, Syrjanen J, Machulda M, Knopman DS, Jack CR Jr, Petersen R, Mielke MM. Sex Differences in the Association Between Midlife Cardiovascular Conditions or Risk Factors With Midlife Cognitive Decline. Neurology. 2022 Feb 8; 98 (6):e623-e632 Epub 2022 Jan 05
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72. Raghavan S, Przybelski SA, Reid RI, Lesnick TG, Ramanan VK, Botha H, Matchett BJ, Murray ME, Reichard RR, Knopman DS, Graff-Radford J, Jones DT, Lowe VJ, Mielke MM, Machulda MM, Petersen RC, Kantarci K, Whitwell JL, Josephs KA, Jack CR Jr, Vemuri P. White matter damage due to vascular, tau, and TDP-43 pathologies and its relevance to cognition. Acta Neuropathol Commun. 2022 Feb 5; 10 (1):16 Epub 2022 Feb 05
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217. Butts AM, Weigand S, Brown PD, Petersen RC, Jack CR Jr, Machulda MM, Cerhan JH. Neurocognition in individuals with incidentally-identified meningioma. J Neurooncol. 2017 Aug; 134 (1):125-132 Epub 2017 May 25
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218. Vassilaki M, Christianson TJ, Mielke MM, Geda YE, Kremers WK, Machulda MM, Knopman DS, Petersen RC, Lowe VJ, Jack CR Jr, Roberts RO. Neuroimaging biomarkers and impaired olfaction in cognitively normal individuals. Ann Neurol. 2017 Jun; 81 (6):871-882 Epub 2017 June 09
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219. Vemuri P, Knopman DS, Lesnick TG, Przybelski SA, Mielke MM, Graff-Radford J, Murray ME, Roberts RO, Vassilaki M, Lowe VJ, Machulda MM, Jones DT, Petersen RC, Jack CR Jr. Evaluation of Amyloid Protective Factors and Alzheimer Disease Neurodegeneration Protective Factors in Elderly Individuals. JAMA Neurol. 2017 Jun 1; 74 (6):718-726
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220. Jack CR Jr, Wiste HJ, Weigand SD, Therneau TM, Knopman DS, Lowe V, Vemuri P, Mielke MM, Roberts RO, Machulda MM, Senjem ML, Gunter JL, Rocca WA, Petersen RC. Age-specific and sex-specific prevalence of cerebral beta-amyloidosis, tauopathy, and neurodegeneration in cognitively unimpaired individuals aged 50-95 years: a cross-sectional study. Lancet Neurol. 2017 Jun; 16 (6):435-444 Epub 2017 Apr 26
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221. Whitwell JL, Duffy JR, Machulda MM, Clark HM, Strand EA, Senjem ML, Gunter JL, Spychalla AJ, Petersen RC, Jack CR Jr, Josephs KA. Tracking the development of agrammatic aphasia: A tensor-based morphometry study. Cortex. 2017 May; 90:138-148 Epub 2016 Sept 30
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222. Josephs KA, Murray ME, Tosakulwong N, Whitwell JL, Knopman DS, Machulda MM, Weigand SD, Boeve BF, Kantarci K, Petrucelli L, Lowe VJ, Jack CR Jr, Petersen RC, Parisi JE, Dickson DW. Tau aggregation influences cognition and hippocampal atrophy in the absence of beta-amyloid: a clinico-imaging-pathological study of primary age-related tauopathy (PART). Acta Neuropathol. 2017 May; 133 (5):705-715 Epub 2017 Feb 03
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223. Carvalho DZ, St Louis EK, Boeve BF, Mielke MM, Przybelski SA, Knopman DS, Machulda MM, Roberts RO, Geda YE, Petersen RC, Jack CR Jr, Vemuri P. Excessive daytime sleepiness and fatigue may indicate accelerated brain aging in cognitively normal late middle-aged and older adults. Sleep Med. 2017 Apr; 32:236-243 Epub 2016 Nov 03
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224. Jack CR Jr, Wiste HJ, Weigand SD, Therneau TM, Lowe VJ, Knopman DS, Gunter JL, Senjem ML, Jones DT, Kantarci K, Machulda MM, Mielke MM, Roberts RO, Vemuri P, Reyes DA, Petersen RC. Defining imaging biomarker cut points for brain aging and Alzheimer's disease. Alzheimers Dement. 2017 Mar; 13 (3):205-216 Epub 2016 Sept 30
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225. Staubo SC, Aakre JA, Vemuri P, Syrjanen JA, Mielke MM, Geda YE, Kremers WK, Machulda MM, Knopman DS, Petersen RC, Jack CR Jr, Roberts RO. Mediterranean diet, micronutrients and macronutrients, and MRI measures of cortical thickness. Alzheimers Dement. 2017 Feb; 13(2):168-177. Epub 2016 Jul 25.
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226. Savica R, Wennberg AM, Hagen C, Edwards K, Roberts RO, Hollman JH, Knopman DS, Boeve BF, Machulda MM, Petersen RC, Mielke MM. Comparison of Gait Parameters for Predicting Cognitive Decline: The Mayo Clinic Study of Aging. J Alzheimers Dis. 2017; 55(2):559-567.
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227. Krishnan K, Machulda MM, Whitwell JL, Butts AM, Duffy JR, Strand EA, Senjem ML, Spychalla AJ, Jack CR, Lowe VJ, Josephs KA. Varying Degrees of Temporoparietal Hypometabolism on FDG-PET Reveal Amyloid-Positive Logopenic Primary Progressive Aphasia is not a Homogeneous Clinical Entity. J Alzheimers Dis. 2017; 55 (3):1019-1029
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228. Machulda MM, Hagen CE, Wiste HJ, Mielke MM, Knopman DS, Roberts RO, Vemuri P, Lowe VJ, Jack CR Jr, Petersen RC. [Formula: see text]Practice effects and longitudinal cognitive change in clinically normal older adults differ by Alzheimer imaging biomarker status. Clin Neuropsychol. 2017 Jan; 31 (1):99-117 Epub 2016 Oct 11
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229. Vemuri P, Lowe VJ, Knopman DS, Senjem ML, Kemp BJ, Schwarz CG, Przybelski SA, Machulda MM, Petersen RC, Jack CR Jr. Tau-PET uptake: Regional variation in average SUVR and impact of amyloid deposition. Alzheimers Dement (Amst). 2017; 6:21-30 Epub 2016 Dec 21
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230. Dage JL, Wennberg AMV, Airey DC, Hagen CE, Knopman DS, Machulda MM, Roberts RO, Jack CR Jr, Petersen RC, Mielke MM. Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population-based elderly cohort. Alzheimers Dement. 2016 Dec; 12 (12):1226-1234 Epub 2016 July 18
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231. Knopman DS, Jack CR Jr, Lundt ES, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC. Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum. Neurobiol Aging. 2016 Oct; 46:32-42 Epub 2016 June 16
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232. Knopman DS, Jack CR Jr, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC. Age and neurodegeneration imaging biomarkers in persons with Alzheimer disease dementia. Neurology. 2016 Aug 16; 87 (7):691-8 Epub 2016 July 15
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233. Krell-Roesch J, Ruider H, Lowe VJ, Stokin GB, Pink A, Roberts RO, Mielke MM, Knopman DS, Christianson TJ, Machulda MM, Jack CR, Petersen RC, Geda YE. FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging. J Alzheimers Dis. 2016 Jul 14; 53 (4):1609-16
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234. Vassilaki M, Aakre JA, Mielke MM, Geda YE, Kremers WK, Alhurani RE, Machulda MM, Knopman DS, Petersen RC, Lowe VJ, Jack CR Jr, Roberts RO. Multimorbidity and neuroimaging biomarkers among cognitively normal persons. Neurology. 2016 May 31; 86 (22):2077-84 Epub 2016 Apr 13
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235. Alhurani RE, Vassilaki M, Aakre JA, Mielke MM, Kremers WK, Machulda MM, Geda YE, Knopman DS, Petersen RC, Roberts RO. Decline in Weight and Incident Mild Cognitive Impairment: Mayo Clinic Study of Aging. JAMA Neurol. 2016 Apr; 73 (4):439-46
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236. Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Machulda M, Lowe VJ, Mielke MM, Roberts RO, Gunter JL, Senjem ML, Geda YE, Rocca WA, Petersen RC, Jack CR Jr. Effect of intellectual enrichment on AD biomarker trajectories: Longitudinal imaging study. Neurology. 2016 Mar 22; 86 (12):1128-35 Epub 2016 Feb 24
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237. Mielke MM, Machulda MM, Hagen CE, Christianson TJ, Roberts RO, Knopman DS, Vemuri P, Lowe VJ, Kremers WK, Jack CR Jr, Petersen RC. Influence of amyloid and APOE on cognitive performance in a late middle-aged cohort. Alzheimers Dement. 2016 Mar; 12 (3):281-91 Epub 2015 Nov 19
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238. Jung Y, Whitwell JL, Duffy JR, Strand EA, Machulda MM, Senjem ML, Jack CR, Lowe VJ, Josephs KA. Regional beta-amyloid burden does not correlate with cognitive or language deficits in Alzheimer's disease presenting as aphasia. Eur J Neurol. 2016 Feb; 23 (2):313-9 Epub 2015 June 23
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239. Petersen RC, Wiste HJ, Weigand SD, Rocca WA, Roberts RO, Mielke MM, Lowe VJ, Knopman DS, Pankratz VS, Machulda MM, Geda YE, Jack CR Jr. Association of Elevated Amyloid Levels With Cognition and Biomarkers in Cognitively Normal People From the Community. JAMA Neurol. 2016 Jan; 73 (1):85-92
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240. Jack CR Jr, Therneau TM, Wiste HJ, Weigand SD, Knopman DS, Lowe VJ, Mielke MM, Vemuri P, Roberts RO, Machulda MM, Senjem ML, Gunter JL, Rocca WA, Petersen RC. Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study. Lancet Neurol. 2016 Jan; 15 (1):56-64 Epub 2015 Nov 18
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241. Whitwell JL, Weigand SD, Duffy JR, Strand EA, Machulda MM, Senjem ML, Gunter JL, Lowe VJ, Jack CR Jr, Josephs KA. Clinical and MRI models predicting amyloid deposition in progressive aphasia and apraxia of speech. Neuroimage Clin. 2016; 11:90-98 Epub 2016 Jan 20
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242. Madhavan A, Schwarz CG, Duffy JR, Strand EA, Machulda MM, Drubach DA, Kantarci K, Przybelski SA, Reid RI, Senjem ML, Gunter JL, Apostolova LG, Lowe VJ, Petersen RC, Jack CR, Josephs KA, Whitwell JL. Characterizing White Matter Tract Degeneration in Syndromic Variants of Alzheimer's Disease: A Diffusion Tensor Imaging Study. J Alzheimers Dis. 2016; 49 (3):633-43
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243. Roberts RO, Christianson TJ, Kremers WK, Mielke MM, Machulda MM, Vassilaki M, Alhurani RE, Geda YE, Knopman DS, Petersen RC. Association Between Olfactory Dysfunction and Amnestic Mild Cognitive Impairment and Alzheimer Disease Dementia. JAMA Neurol. 2016 Jan; 73 (1):93-101
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244. Jack CR Jr, Wiste HJ, Weigand SD, Knopman DS, Mielke MM, Vemuri P, Lowe V, Senjem ML, Gunter JL, Reyes D, Machulda MM, Roberts R, Petersen RC. Different definitions of neurodegeneration produce similar amyloid/neurodegeneration biomarker group findings. Brain. 2015 Dec; 138 (Pt 12):3747-59 Epub 2015 Sept 30
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245. Knopman DS, Jack CR Jr, Lundt ES, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC. Role of beta-Amyloidosis and Neurodegeneration in Subsequent Imaging Changes in Mild Cognitive Impairment. JAMA Neurol. 2015 Dec; 72 (12):1475-83
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246. Knopman DS, Beiser A, Machulda MM, Fields J, Roberts RO, Pankratz VS, Aakre J, Cha RH, Rocca WA, Mielke MM, Boeve BF, Devine S, Ivnik RJ, Au R, Auerbach S, Wolf PA, Seshadri S, Petersen RC. Spectrum of cognition short of dementia: Framingham Heart Study and Mayo Clinic Study of Aging. Neurology. 2015 Nov 10; 85 (19):1712-21 Epub 2015 Oct 09
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247. Mielke MM, Machulda MM, Hagen CE, Edwards KK, Roberts RO, Pankratz VS, Knopman DS, Jack CR Jr, Petersen RC. Performance of the CogState computerized battery in the Mayo Clinic Study on Aging. Alzheimers Dement. 2015 Nov; 11(11):1367-76. Epub 2015 Apr 06.
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248. Vassilaki M, Aakre JA, Cha RH, Kremers WK, St Sauver JL, Mielke MM, Geda YE, Machulda MM, Knopman DS, Petersen RC, Roberts RO. Multimorbidity and Risk of Mild Cognitive Impairment. J Am Geriatr Soc. 2015 Sep; 63 (9):1783-90 Epub 2015 Aug 27
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249. Whitwell JL, Duffy JR, Strand EA, Machulda MM, Tosakulwong N, Weigand SD, Senjem ML, Spychalla AJ, Gunter JL, Petersen RC, Jack CR Jr, Josephs KA. Sample size calculations for clinical trials targeting tauopathies: a new potential disease target. J Neurol. 2015 Sep; 262 (9):2064-72 Epub 2015 June 17
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250. Botha H, Duffy JR, Whitwell JL, Strand EA, Machulda MM, Schwarz CG, Reid RI, Spychalla AJ, Senjem ML, Jones DT, Lowe V, Jack CR, Josephs KA. Classification and clinicoradiologic features of primary progressive aphasia (PPA) and apraxia of speech. Cortex. 2015 Aug; 69:220-36 Epub 2015 May 27
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251. Butts AM, Machulda MM, Duffy JR, Strand EA, Whitwell JL, Josephs KA. Neuropsychological Profiles Differ among the Three Variants of Primary Progressive Aphasia. J Int Neuropsychol Soc. 2015 Jul; 21 (6):429-35 Epub 2015 June 11
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252. Black DF, DeLone DR, Kaufmann TJ, Fitz-Gibbon PD, Carter RE, Machulda MM, Welker KM. Retrospective Analysis of Interobserver Spatial Variability in the Localization of Broca's and Wernicke's Areas Using Three Different fMRI Language Paradigms. J Neuroimaging. 2015 Jul-Aug; 25: (4)626-33.
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253. Singh TD, Josephs KA, Machulda MM, Drubach DA, Apostolova LG, Lowe VJ, Whitwell JL. Clinical, FDG and amyloid PET imaging in posterior cortical atrophy. J Neurol. 2015 Jun; 262 (6):1483-92 Epub 2015 Apr 11
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254. Roberts RO, Cha RH, Mielke MM, Geda YE, Boeve BF, Machulda MM, Knopman DS, Petersen RC. Risk and protective factors for cognitive impairment in persons aged 85 years and older. Neurology. 2015 May 5; 84 (18):1854-61 Epub 2015 Apr 08
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255. Jack CR Jr, Wiste HJ, Weigand SD, Knopman DS, Vemuri P, Mielke MM, Lowe V, Senjem ML, Gunter JL, Machulda MM, Gregg BE, Pankratz VS, Rocca WA, Petersen RC. Age, Sex, and APOE epsilon4 Effects on Memory, Brain Structure, and beta-Amyloid Across the Adult Life Span. JAMA Neurol. 2015 May; 72 (5):511-9
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256. Pink A, Stokin GB, Bartley MM, Roberts RO, Sochor O, Machulda MM, Krell-Roesch J, Knopman DS, Acosta JI, Christianson TJ, Pankratz VS, Mielke MM, Petersen RC, Geda YE. Neuropsychiatric symptoms, APOE epsilon4, and the risk of incident dementia: a population-based study. Neurology. 2015 Mar 3; 84 (9):935-43 Epub 2015 Feb 04
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257. Whitwell JL, Jones DT, Duffy JR, Strand EA, Machulda MM, Przybelski SA, Vemuri P, Gregg BE, Gunter JL, Senjem ML, Petersen RC, Jack CR Jr, Josephs KA. Working memory and language network dysfunctions in logopenic aphasia: a task-free fMRI comparison with Alzheimer's dementia. Neurobiol Aging. 2015 Mar; 36 (3):1245-52 Epub 2014 Dec 16
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258. Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Preboske GM, Kantarci K, Raman MR, Machulda MM, Mielke MM, Lowe VJ, Senjem ML, Gunter JL, Rocca WA, Roberts RO, Petersen RC, Jack CR Jr. Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly. Brain. 2015 Mar; 138 (Pt 3):761-71 Epub 2015 Jan 15
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259. Whitwell JL, Duffy JR, Strand EA, Machulda MM, Senjem ML, Schwarz CG, Reid R, Baker MC, Perkerson RB, Lowe VJ, Rademakers R, Jack CR Jr, Josephs KA. Clinical and neuroimaging biomarkers of amyloid-negative logopenic primary progressive aphasia. Brain Lang. 2015 Mar; 142:45-53 Epub 2015 Feb 03
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260. Duffy JR, Strand EA, Clark H, Machulda M, Whitwell JL, Josephs KA. Primary progressive apraxia of speech: Clinical features and acoustic and neurologic correlates. Am J Speech Lang Pathol. 2015; 24(2):88-100.
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261. Singh TD, Duffy JR, Strand EA, Machulda MM, Whitwell JL, Josephs KA. Neuropsychiatric symptoms in primary progressive aphasia and apraxia of speech. Dement Geriatr Cogn Disord. 2015; 39 (3-4):228-38 Epub 2015 Jan 21
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262. Flanagan EP, Baker MC, Perkerson RB, Duffy JR, Strand EA, Whitwell JL, Machulda MM, Rademakers R, Josephs KA. Dominant frontotemporal dementia mutations in 140 cases of primary progressive aphasia and speech apraxia. Dement Geriatr Cogn Disord. 2015; 39 (5-6):281-6 Epub 2015 Feb 28
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263. Whitwell JL, Kantarci K, Weigand SD, Lundt ES, Gunter JL, Duffy JR, Strand EA, Machulda MM, Spychalla AJ, Drubach DA, Petersen RC, Lowe VJ, Jack CR Jr, Josephs KA. Microbleeds in atypical presentations of Alzheimer's disease: a comparison to dementia of the Alzheimer's type. J Alzheimers Dis. 2015; 45(4):1109-17.
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264. Carrasquillo MM, Crook JE, Pedraza O, Thomas CS, Pankratz VS, Allen M, Nguyen T, Malphrus KG, Ma L, Bisceglio GD, Roberts RO, Lucas JA, Smith GE, Ivnik RJ, Machulda MM, Graff-Radford NR, Petersen RC, Younkin SG, Ertekin-Taner N. Late-onset Alzheimer's risk variants in memory decline, incident mild cognitive impairment, and Alzheimer's disease. Neurobiol Aging. 2015 Jan; 36 (1):60-7 Epub 2014 Aug 04
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265. Zhao Q, Roberts RO, Ding D, Cha R, Guo Q, Meng H, Luo J, Machulda MM, Shane Pankratz V, Wang B, Christianson TJ, Aakre JA, Knopman DS, Boeve BF, Hong Z, Petersen RC, Shanghai Aging Study (SAS)//Mayo Clinic Study of Aging (MCSA). Diabetes is Associated with Worse Executive Function in Both Eastern and Western Populations: Shanghai Aging Study and Mayo Clinic Study of Aging. J Alzheimers Dis. 2015; 47 (1):167-76
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266. Kantarci K, Schwarz CG, Reid RI, Przybelski SA, Lesnick TG, Zuk SM, Senjem ML, Gunter JL, Lowe V, Machulda MM, Knopman DS, Petersen RC, Jack CR Jr. White matter integrity determined with diffusion tensor imaging in older adults without dementia: influence of amyloid load and neurodegeneration. JAMA Neurol. 2014 Dec; 71 (12):1547-54
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267. Mielke MM, Weigand SD, Wiste HJ, Vemuri P, Machulda MM, Knopman DS, Lowe V, Roberts RO, Kantarci K, Rocca WA, Jack CR Jr, Petersen RC. Independent comparison of CogState computerized testing and a standard cognitive battery with neuroimaging. Alzheimers Dement. 2014 Nov; 10 (6):779-89 Epub 2014 Nov 15
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268. Josephs KA, Duffy JR, Strand EA, Machulda MM, Senjem ML, Lowe VJ, Jack CR Jr, Whitwell JL. APOE epsilon4 influences beta-amyloid deposition in primary progressive aphasia and speech apraxia. Alzheimers Dement. 2014 Nov; 10 (6):630-6 Epub 2014 June 28
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269. Josephs KA, Duffy JR, Strand EA, Machulda MM, Senjem ML, Gunter JL, Schwarz CG, Reid RI, Spychalla AJ, Lowe VJ, Jack CR Jr, Whitwell JL. The evolution of primary progressive apraxia of speech. Brain. 2014 Oct; 137 (Pt 10):2783-95 Epub 2014 Aug 11
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270. Vemuri P, Lesnick TG, Przybelski SA, Machulda M, Knopman DS, Mielke MM, Roberts RO, Geda YE, Rocca WA, Petersen RC, Jack CR Jr. Association of lifetime intellectual enrichment with cognitive decline in the older population. JAMA Neurol. 2014 Aug; 71 (8):1017-24
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271. Jung Y, Whitwell JL, Duffy JR, Strand EA, Machulda MM, Senjem ML, Lowe V, Jack CR Jr, Josephs KA. Amyloid burden correlates with cognitive decline in Alzheimer's disease presenting with aphasia. Eur J Neurol. 2014 Jul; 21 (7):1040-3 Epub 2013 Dec 16
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272. Botha H, Duffy JR, Strand EA, Machulda MM, Whitwell JL, Josephs KA. Nonverbal oral apraxia in primary progressive aphasia and apraxia of speech. Neurology. 2014 May 13; 82 (19):1729-35 Epub 2014 Apr 11
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273. Wicklund MR, Duffy JR, Strand EA, Machulda MM, Whitwell JL, Josephs KA. Quantitative application of the primary progressive aphasia consensus criteria. Neurology. 2014 Apr 1; 82 (13):1119-26 Epub 2014 Mar 05
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274. Josephs KA, Duffy JR, Strand EA, Machulda MM, Vemuri P, Senjem ML, Perkerson RB, Baker MC, Lowe V, Jack CR Jr, Rademakers R, Whitwell JL. Progranulin-associated PiB-negative logopenic primary progressive aphasia. J Neurol. 2014 Mar; 261 (3):604-14 Epub 2014 Jan 22
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275. Mielke MM, Savica R, Wiste HJ, Weigand SD, Vemuri P, Knopman DS, Lowe VJ, Roberts RO, Machulda MM, Geda YE, Petersen RC, Jack CR Jr. Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study. Neurology. 2014 Jan 07; 82(1):70-6. Epub 2013 Dec 26.
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276. Whitwell JL, Jack CR Jr, Duffy JR, Strand EA, Gunter JL, Senjem ML, Murphy MC, Kantarci K, Machulda MM, Lowe VJ, Josephs KA. Microbleeds in the logopenic variant of primary progressive aphasia. Alzheimers Dement. 2014 Jan; 10 (1):62-6 Epub 2013 Apr 03
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277. Whitwell JL, Lowe VJ, Duffy JR, Strand EA, Machulda MM, Kantarci K, Wille SM, Senjem ML, Murphy MC, Gunter JL, Jack CR Jr, Josephs KA. Elevated occipital beta-amyloid deposition is associated with widespread cognitive impairment in logopenic progressive aphasia. J Neurol Neurosurg Psychiatry. 2013 Dec; 84 (12):1357-64 Epub 2013 Aug 14
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278. Machulda MM, Whitwell JL, Duffy JR, Strand EA, Dean PM, Senjem ML, Jack CR Jr, Josephs KA. Identification of an atypical variant of logopenic progressive aphasia. Brain Lang. 2013 Nov; 127 (2):139-44 Epub 2013 Apr 06
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279. Adeli A, Drubach DA, Machulda MM. Resolution of neuropsychological and FDG-PET abnormalities in a patient with neuropsychiatric systemic lupus erythematosus. Cogn Behav Neurol. 2013 Sep; 26 (3):161-6
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280. Josephs KA, Papenfuss SM, Duffy JR, Strand EA, Machulda MM, Whitwell JL, Petersen RC. Occupational differences between Alzheimer's and aphasic dementias: implication for teachers. Am J Alzheimers Dis Other Demen. 2013 Sep; 28 (6):612-6 Epub 2013 July 09
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281. Wicklund MR, Duffy JR, Strand EA, Whitwell JL, Machulda MM, Josephs KA. Aphasia with left occipitotemporal hypometabolism: a novel presentation of posterior cortical atrophy? J Clin Neurosci. 2013 Sep; 20 (9):1237-40 Epub 2013 July 11
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282. Mielke MM, Roberts RO, Savica R, Cha R, Drubach DI, Christianson T, Pankratz VS, Geda YE, Machulda MM, Ivnik RJ, Knopman DS, Boeve BF, Rocca WA, Petersen RC. Assessing the temporal relationship between cognition and gait: slow gait predicts cognitive decline in the Mayo Clinic Study of Aging. J Gerontol A Biol Sci Med Sci. 2013 Aug; 68 (8):929-37 Epub 2012 Dec 18
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283. Josephs KA, Duffy JR, Strand EA, Machulda MM, Senjem ML, Lowe VJ, Jack CR Jr, Whitwell JL. Syndromes dominated by apraxia of speech show distinct characteristics from agrammatic PPA. Neurology. 2013 Jul 23; 81 (4):337-45 Epub 2013 June 26
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284. Kantarci K, Weigand SD, Przybelski SA, Preboske GM, Pankratz VS, Vemuri P, Senjem ML, Murphy MC, Gunter JL, Machulda MM, Ivnik RJ, Roberts RO, Boeve BF, Rocca WA, Knopman DS, Petersen RC, Jack CR Jr. MRI and MRS predictors of mild cognitive impairment in a population-based sample. Neurology. 2013 Jul 9; 81 (2):126-33 Epub 2013 June 12
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285. Whitwell JL, Duffy JR, Strand EA, Xia R, Mandrekar J, Machulda MM, Senjem ML, Lowe VJ, Jack CR Jr, Josephs KA. Distinct regional anatomic and functional correlates of neurodegenerative apraxia of speech and aphasia: an MRI and FDG-PET study. Brain Lang. 2013 Jun; 125 (3):245-52 Epub 2013 Mar 28
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286. Whitwell JL, Duffy JR, Strand EA, Machulda MM, Senjem ML, Gunter JL, Kantarci K, Eggers SD, Jack CR Jr, Josephs KA. Neuroimaging comparison of primary progressive apraxia of speech and progressive supranuclear palsy. Eur J Neurol. 2013 Apr; 20 (4):629-37 Epub 2012 Oct 18
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287. Machulda MM, Pankratz VS, Christianson TJ, Ivnik RJ, Mielke MM, Roberts RO, Knopman DS, Boeve BF, Petersen RC. Practice effects and longitudinal cognitive change in normal aging vs. incident mild cognitive impairment and dementia in the Mayo Clinic Study of Aging. Clin Neuropsychol. 2013; 27 (8):1247-64 Epub 2013 Sept 17
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288. Madhavan A, Whitwell JL, Weigand SD, Duffy JR, Strand EA, Machulda MM, Tosakulwong N, Senjem ML, Gunter JL, Lowe VJ, Petersen RC, Jack CR Jr, Josephs KA. FDG PET and MRI in logopenic primary progressive aphasia versus dementia of the Alzheimer's type. PLoS One. 2013; 8 (4):e62471 Epub 2013 Apr 23
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289. Welker KM, De Jesus RO, Watson RE, Machulda MM, Jack CR. Altered functional MR imaging language activation in elderly individuals with cerebral leukoaraiosis. Radiology. 2012 Oct; 265(1):222-32. Epub 2012 Aug 13.
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290. Josephs KA, Duffy JR, Strand EA, Machulda MM, Senjem ML, Master AV, Lowe VJ, Jack CR Jr, Whitwell JL. Characterizing a neurodegenerative syndrome: primary progressive apraxia of speech. Brain. 2012 May; 135 (Pt 5):1522-36 Epub 2012 Mar 01
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291. Boeve BF, Boylan KB, Graff-Radford NR, DeJesus-Hernandez M, Knopman DS, Pedraza O, Vemuri P, Jones D, Lowe V, Murray ME, Dickson DW, Josephs KA, Rush BK, Machulda MM, Fields JA, Ferman TJ, Baker M, Rutherford NJ, Adamson J, Wszolek ZK, Adeli A, Savica R, Boot B, Kuntz KM, Gavrilova R, Reeves A, Whitwell J, Kantarci K, Jack CR Jr, Parisi JE, Lucas JA, Petersen RC, Rademakers R. Characterization of frontotemporal dementia and/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72. Brain. 2012 Mar; 135 (Pt 3):765-83
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292. Jones DT, Vemuri P, Murphy MC, Gunter JL, Senjem ML, Machulda MM, Przybelski SA, Gregg BE, Kantarci K, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr. Non-stationarity in the "resting brain's" modular architecture. PLoS One. 2012; 7 (6):e39731 Epub 2012 June 28
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293. Jones DT, Machulda MM, Vemuri P, McDade EM, Zeng G, Senjem ML, Gunter JL, Przybelski SA, Avula RT, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr. Age-related changes in the default mode network are more advanced in Alzheimer disease. Neurology. 2011 Oct 18; 77 (16):1524-31 Epub 2011 Oct 05
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294. Machulda MM, Jones DT, Vemuri P, McDade E, Avula R, Przybelski S, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr. Effect of APOE epsilon4 status on intrinsic network connectivity in cognitively normal elderly subjects. Arch Neurol. 2011 Sep; 68 (9):1131-6 Epub 2011 May 09
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295. Fields JA, Machulda M, Aakre J, Ivnik RJ, Boeve BF, Knopman DS, Petersen RC, Smith GE. Utility of the DRS for predicting problems in day-to-day functioning. Clin Neuropsychol. 2010 Oct; 24(7):1167-80.
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297. Machulda MM, Ivnik RJ, Smith GE, Ferman TJ, Boeve BF, Knopman D, Petersen RC, Tangalos EG. "Mayo's older Americans normative studies: Visual form discrimination and copy trial of the Rey-Osterrieth Complex Figure": Corrigendum. J Clin Exp Neuropsychol. 2008; 30(1):132.
     
298. Smith GE, Pankratz VS, Negash S, Machulda MM, Petersen RC, Boeve BF, Knopman DS, Lucas JA, Ferman TJ, Graff-Radford N, Ivnik RJ. A plateau in pre-Alzheimer memory decline: evidence for compensatory mechanisms? Neurology. 2007 Jul 10; 69 (2):133-9
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299. Machulda MM, Ivnik RJ, Smith GE, Ferman TJ, Boeve BF, Knopman D, Knopman D, Petersen RC, Tangalos EG. Mayo's Older Americans Normative Studies: Visual Form Discrimination and copy trial of the Rey-Osterrieth Complex Figure. J Clin Exp Neuropsychol. 2007 May; 29 (4):377-84
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300. Cerhan JH, Ivnik RJ, Smith GE, Machulda MM, Boeve BF, Knopman DS, Petersen RC, Tangalos EG. Alzheimer's disease patients' cognitive status and course years prior to symptom recognition. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2007 May; 14 (3):227-35
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301. Machulda MM, Ward HA, Borowski B, Gunter JL, Cha RH, O'Brien PC, Petersen RC, Boeve BF, Knopman D, Tang-Wai DF, Ivnik RJ, Smith GE, Tangalos EG, Jack CR Jr. Comparison of memory fMRI response among normal, MCI, and Alzheimer's patients. Neurology. 2003 Aug 26; 61(4):500-6.
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302. Machulda MM, Ward HA, Cha R, O'Brien P, Jack CR Jr. Functional inferences vary with the method of analysis in fMRI. Neuroimage. 2001 Nov; 14 (5):1122-7
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303. Machulda MM, Bergquist TF, Ito V, Chew S. Relationship between stress, coping, and postconcussion symptoms in a healthy adult population. Arch Clin Neuropsychol. 1998 Jul; 13(5):415-24.
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304. Malec JF, Machulda MM, Moessner AM. Differing problem perceptions of staff, survivors, and significant others after brain injury. J Head Trauma Rehabil. 1997; 12(3):1-13.
     
305. Malec JF, Machulda MM, Smigielski JS. Cluster analysis of neuropsychological tests among patients with traumatic brain injury (TBI): implications for a model of TBI-related disability. Clin Neuropsychol. 1993; 1:48-58.
     
306. Shen WK, Tung RT, Machulda MM, Kurachi Y. Essential role of nucleotide diphosphates in nicorandil-mediated activation of cardiac ATP-sensitive K+ channel. A comparison with pinacidil and lemakalim. Circ Res. 1991 Oct; 69 (4):1152-8
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