Ensayos clínicos

The purpose of this study is to evaluate the effectiveness of SoftStitch™ for All-Inside Meniscal Repair of longitudinal tears on the posterior horn, and to observe improvement for ePROM and functional assessments of the knee at 24 months follow-up when compared to baseline.

The secondary objective is to assess complications related to SoftStitch™, retears and repeated surgery. Structural healing of the meniscus will be evaluated at 6 months with MRI. Also, the safety profile of SoftStitch™ for All-Inside Meniscal Repair will be observed.

Horizontal meniscus tears meeting specified criteria will be repaired by any commonly used suture technique. Subjects will be followed for 2 years to evaluate the effectiveness of the repair, by assessing the re-operation rate, and by assessing improvements in knee pain and knee function.

The primary objective of this study is to compare post-operative patient reported outcome measures of Bone Marrow Venting Procedure (BMVP) versus Platelet Rich Plasma (PRP) augmented meniscal repair.

The secondary objective is to compare outcomes of BMVP versus PRP as related to meniscal repair failure.

The results of this study will optimize the care for patients with a meniscus root tear. Surgeons will be able to determine if MRR (meniscus root repair) with transtibial pullout technique is an effective treatment and will identify potential risk factors for poor clinical outcomes. In addition, investigators will determine if MRR is successful in delaying the radiographic progression of arthritis in the involved compartment.

The purpose of this study is to see if the inflammation in early stage arthritis can be cessated by changing synoviocyte-macrophage interactions in a way that macrophages do not get activated.