Lung nodule

Displaying 12 studies

  • A Multicenter Study to Evaluate the Cios Spin and the Ion Endoluminal System for Pulmonary Nodule Biopsy Rochester, MN

    The overall objective of this study is to evaluate procedure characteristics of pulmonary nodule biopsies using the integrated version of Cios Spin and the Ion Endoluminal System.

  • Nodify XL2 Classifier Clinical Utility Study in Low to Moderate Risk Lung Nodules Rochester, MN

    The purpose of this study is to show a reduction in the proportion of benign lung nodules experiencing invasive procedures (biopsies or surgery) between a group of patients managed by standard of care with Nodify XL2 results and a group managed by standard of care blinded from Nodify XL2 results.

  • OTL38 for Intraoperative Imaging of Folate Receptor Positive Lung Nodules No Locations

    The purpose of this study is to assess the effectiveness of OTL38 and Near Infrared Imaging (NIR) at identifying pulmonary nodules within the operating theater, and to assess the safety and tolerability of single intravenous doses of OTL38.

  • A Study Using a New Ultra-low Dose CT Scanner to Find Lung Nodules Rochester, MN

    The purpose of this study is to test the use of ultra-low dose CT scans to find lung nodules compared to the standard routine low dose CT scans.

  • MRI of Lung Spots Rochester, MN

    The purpose of this study is to see if magnetic resonance imaging (MRI) can determine the cause of these lung nodules.

  • Feasibility of Performing Peripheral Pulmonary Lesion Biopsy Using Robotic Bronchoscopy-Guided Cryoprobe Rochester, MN

    The purpose of this randomized control study is to evaluate the feasibility of using a miniature (1.1 mm) cryoprobe to perform biopsy of peripheral pulmonary lesions using robotic bronchoscopy.

  • A Multi-Center Trial of the ProLung Test™ Rochester, MN

    The primary Study hypothesis is that the ProLung Test will demonstrate safety and efficacy in the risk stratification of patients with pulmonary lesions identified by CT that are suspicious for lung cancer. A statistically significant result will indicate that patients with a high ProLung Test result have a greater risk of developing lung cancer than patients with a low test result. There are three Specific Aims of this study: 1. Optimize and confirm the stability of the ProLung Test risk-stratification algorithm in patients with a diagnosis. 2. Externally validate the efficacy of the ProLung Test risk-stratification algorithm by comparing the ...

  • Identification of a Plasma Proteomic Signature for Lung Cancer Scottsdale/Phoenix, AZ; Rochester, MN

    The primary objective is to identify a panel of plasma and/or serum proteins that differentiates the absence or presence of lung malignancy in samples obtained from subjects enrolled in this IRB/EC approved study with pulmonary nodules.

  • A Study to Predict Lung Cancer Using Noninvasive Biomarkers Rochester, MN

    The purpose of this study is to improve the efficiency of the diagnostic evaluation of patients with indeterminate pulmonary nodules.

  • A Study to Evaluate the Clinical Utility for the Ion™ Endoluminal System Rochester, MN

    The purpose of this study is to evaluate the clinical utility and early performance of the FDA cleared Ion™ Endoluminal System (“Ion”) for brochoscopically approaching and facilitating the sampling of peripheral pulmonary nodules, between 1-3cm in size, of unknown etiology.

  • A Study to Collect Medical Data and Tissue from Patients with Lung Conditions Resulting in Lung Surgery. Rochester, MN

    The purpose of this study is to collect lung tissue and blood samples from participants who undergo medically-indicated lung surgery and maintain a bank of specimens from a wide range of participants with varying types of lung disease and progressions.   

  • A Study to Collect Thoracic Specimens to Develop a Thoracic Specimen Registry Rochester, MN; Scottsdale/Phoenix, AZ

    The primary objective of this proposal is to develop a Thoracic Specimen Registry at Mayo Clinic. The purpose of the registry will be to support ongoing research in the etiology, early diagnosis, clinical management, and prognosis of lung cancer and other cancers and diseases of the thorax by developing a complete repository of specimens from patients with thoracic disease including but not limited to suspected lung cancer, mediastinal and pleural tumors and from patients at a very high risk of developing other thoracic cancers or other thoracic diseases. 

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