Ensayos clínicos

The purpose of this study is to assess the ability of the hyperphagia questionnaires to identify children and young adults with early-onset obesity for genetic testing to identify variants in 36 genes of interest associated with MC4R pathway genetic obesity

Approximately one third of the children and adolescents in the United States are either overweight or obese. Childhood obesity disproportionately affects specific racial and ethnic groups and households with low socioeconomic status and low parental education. The Alternative Learning Center (ALC) within Rochester School District 535 provides viable educational options for students who are experiencing difficulty in regular educational systems. A greater proportion of students at ALC are minorities, qualify for free and reduced lunch and receive special education services. These children are likely to have unique barriers to physical activity and healthy eating.

Specific Aims:

Aim 1: ...

The purpose of this extension study of up to an additional 2 years duration beyond the index trial for patients who have completed a previous study of setmelanotide for genetic obesity disorders upstream of the MC4 receptor in the melanocortin-leptin pathway. Since continued assessments of the safety and efficacy of setmelanotide are the same in this extension protocol regardless of the disease studied in the index protocol, all patients can be followed in this single extension protocol. Nevertheless, the analysis of each individual disease will be performed separately with the ability to combine data from the original index protocol and ...

FIT is grounded in social cognitive, self-determination, and family systems theories and, as such, aims to promote healthy eating and movement habits by facilitating the development of parent-adolescent communication and problem-solving skills to support the adolescents’ and family’s pursuit of health behavior change goals.

The purpose of this study is to examine whether an education program, designed in partnership with teachers at Moreland Elementary School in West St. Paul and Mayo Clinic InSciEd Out scientists, is able to influence the behavior and health literacy of students. This information will be collected in surveys before and after the students are given the curriculum during the school day.

The primary purpose of this study is to develop a screening system for factors that impact growth in infants within the newborn nursery, as well as a feeding assessment survey to be completed at well child visits during the first 12 months of life.

Vitamin D deficiency has been linked to endothelial dysfunction in adults. Obese adolescents have a high prevalence of Vitamin D deficiency as well as evidence of endothelial dysfunction. Our hypothesis is that supplementation of Vitamin D deficient adolescents with Vitamin D would lead to improvement in endothelial dysfunction.

The purpose of this study is to increase the measurement of BMI and WC in the overweight (BMI at or greater than the 85th percentile) and obese (BMI at or greater than 95th percentile) outpatient pediatric population ages 6-19 at Mayo Clinic Rochester and surrounding satellite clinics.  Educate providers and nursing staff on the importance and technique of measuring the WC in the overweight and obese outpatient pediatric population with at least a yearly WC  on every child with a BMI at or greater than the 85th percentile.  Determine the prevalence of various components of the metabolic syndrome (MS) including ...

The purpose of this study is to see if there is a connection between bad experiences in the patient's childhood, either by the patient or the parent, and poor blood sugar control, obesity, poor blood lipid levels, and depression in patients with type 1 diabetes.