Monitoring Body Composition Changes in High Risk Patients for Pancreatic Cancer (PDAC)

Overview

Información sobre este estudio

The purpose of this research is to monitor body composition changes with wearable devices in patients who have been identified as high risk for developing pancreatic cancer (PDAC).

 

Elegibilidad para la participación

Los requisitos de elegibilidad de los participantes incluyen la edad, el sexo, el tipo y el estadio de la enfermedad, y los problemas de salud o tratamientos previos. Las pautas difieren de un estudio a otro e identifican quiénes pueden o no pueden participar. No hay garantía de que cada persona elegible que desee participar en un ensayo se inscribirá. Comunícate con el equipo del estudio para analizar la elegibilidad del estudio y la posible participación.

Inclusion Criteria:

  • Aged 60 and over AND identified as being at high risk for PDAC at the discretion of the PI or by at least one of the following criteria:
    • 2+ relatives with PDAC on same side of family where 2 affected are first degree related to each other and at least 1 affected is first degree related to subject; age 50+ or ≤10 years younger than earliest PDAC in family at time of diagnosis;
    • 2 affected first degree relatives with PDAC; age 50+ or 10 years younger than earliest PDAC in family;
    • BRCA1, BRCA2, PALB2, ATM, MLH1, MSH2, MSH6, PMS2, EPCAM pathogenic or likely pathogenic variant AND 1 first or second degree relative with PDAC; age 50+ or 10 years younger than earliest PDAC in family;
    • Familial Atypical Moles and Malignant Melanoma (FAMMM) with pathogenic or likely pathogenic CDKN2A variant; age 40+;
    • Peutz-Jegher syndrome with STK11 pathogenic or likely pathogenic variant; age 35+;
    • Hereditary pancreatitis with PRSS1 pathogenic or likely pathogenic variant and history of pancreatitis; age 40+.

Exclusion Criteria:

  • Under the age of 60.
  • Pregnancy (to be confirmed by the patient, no pregnancy test is needed.
  • Inclusion/exclusion age increased to 60 as most high risk PDAC patients are older).
  • Individuals with pacemakers.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 9/26/23. Questions regarding updates should be directed to the study team contact.

Sedes participantes de Mayo Clinic

Los estatus de los estudios cambian con frecuencia. Comunícate con el equipo del estudio para obtener la información más actualizada acerca de la posibilidad de participar.

Sede de Mayo Clinic Estatus Contacto

Jacksonville, Fla.

Investigador principal de Mayo Clinic

Yan Bi, M.D., M.B.

Cerrado; inscripción por invitación

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El estudio no está abierto para todos los que cumplen con los criterios de elegibilidad, sino solamente para las personas que el equipo del estudio ha invitado a participar.

Contact information:

Yan Bi M.D., M.B.

(904) 953-6970

Bi.Yan@mayo.edu

More information

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CLS-20555490

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