Ensayos clínicos

Inclusion Criteria:

- Healthy, non-obese, non-pregnant volunteers.

- 1:1 Male/Female Ratio.

- BMI < 30 kg/m^2.

Exclusion Criteria:

- Diabetes.

- Uncontrolled hypertension (with BP measured > 140/90mmHg in the CRTU)

- BMI ≥ 30 kg/m^2.

- Chronic NSAID use (> 1 day/week).

- Use of oral antibiotics for 2 weeks prior to and during the entire 5 day study period.

- Known intolerance of castor oil.

- Diagnosis of gastrointestinal diseases that are associated with abnormal intestinal or
colonic permeability such as inflammatory bowel diseases, irritable bowel syndrome and
celiac disease.

- Prior intestinal or colonic resection.

- Participation in highly vigorous exercise such as running > 5 miles per day in week
prior to the permeability test.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 3/4/2024. Questions regarding updates should be directed to the study team contact.