Find trials
Consejos para buscar

Eosinophil/Asthma Study

Overview

Información sobre este estudio

The objectives of this study are to correlate concentrations of EDN in serum with peripheral blood eosinophil counts, to compare sensitivity and specificity of serum EDN and peripheral blood eosinophil counts for diagnosis of asthma, and to compare correlation of serum EDN and eosinophil counts with asthma disease severity.  Data collected during this study will submittted to the FDAU and used to support the end goal of FDA approval for this device. 

 

Elegibilidad para la participación

Los requisitos de elegibilidad de los participantes incluyen la edad, el sexo, el tipo y el estadio de la enfermedad, y los problemas de salud o tratamientos previos. Las pautas difieren de un estudio a otro e identifican quiénes pueden o no pueden participar. No hay garantía de que cada persona elegible que desee participar en un ensayo se inscribirá. Comunícate con el equipo del estudio para analizar la elegibilidad del estudio y la posible participación.

Inclusion Criteria - Study Arm 1 Preschool Children < 6 years old Asthma Group (N=200) :

  • Diagnosis of asthma.
  • In the absence of an asthma diagnosis:
    • Persistent wheezing of at least one year;
    • Even distribution of socio-demographics including age, gender, race and ethnicity.

Exclusion Criteria:

  • Actively sick with covid or flu.

Inclusion Criteria - Non-Asthma/Disease Controls (N=200) :

  • Diagnosis of allergy.
  • Even distribution of sociodemographics including age, gender, race and ethnicity.

Exclusion Criteria:

  • Diagnosis of asthma.
  • Recurrent wheezing.
  • Actively sick with covid or flu.

Inclusion Criteria - Healthy Controls (N=200) : 

  • Not having or suspected of having any known upper/lower respiratory disease.
  • Even distribution of sociodemographics including age, gender, race and ethnicity.

Exclusion Criteria:

  • Diagnosis of asthma or any known upper/lower respiratory disease.
  • Diagnosis of allergy.
  • Actively sick with covid or flu.

Inclusion Criteria - Study Arm 2 Children 6-17 years of age Asthma Group (N=200) :

  • Diagnosis of asthma.
  • In the absence of an asthma diagnosis:
    • Persistent wheezing of at least one year.
  • Even distribution of sociodemographics including age, gender, race and ethnicity.

Exclusion Criteria:

  • Actively sick with covid or flu.  

Inclusion Criteria - Non-Asthma/Disease Controls  (N=200) :

  • Diagnosis of allergy. 
  • Even distribution of sociodemographics including age, gender, race and ethnicity.

Exclusion Criteria: 

  • Diagnosis of asthma.
  • Recurrent wheezing.
  • Actively sick with covid or flu.

Inclusion Criteria - Healthy Controls  (N=200) :

  •  Not having or suspected of having any known upper/lower respiratory disease.
  • Even distribution of sociodemographics including age, gender, race and ethnicity. 

Exclusion Criteria: 

  • Diagnosis of asthma or recurrent wheezing.
  • Diagnosis of allergy.
  • Actively sick with covid or flu.

Inclusion Criteria - Study Arm 3  Adults > 18 years old
Asthma Group (N=200) :

  • Diagnosis of asthma.
  • Even distribution of sociodemographics including age, gender, race and ethnicity. 

Exclusion Criteria: 

  • Actively sick with covid or flu.  

Inclusion Criteria - Non-Asthma/Disease Controls (N=200) :

  • Diagnosis of allergy.
  • Even distribution of sociodemographics including age, gender, race and ethnicity. 

Exclusion Criteria:

  • Diagnosis of asthma.
  • Recurrent wheezing.
  • Actively sick with covid or flu.

Inclusion Criteria - Healthy Controls  (N=200) :

  •  Not having or suspected of having any known upper/lower respiratory disease.
  • Even distribution of socio-demographics including age, gender, race and ethnicity.

Exclusion Criteriao: 

  • Diagnosis of asthma.
  • Diagnosis of allergy.
  • Actively sick with covid or flu.

Eligibility last updated 11/2/22. Questions regarding updates should be directed to the study team contact.

 

 

Sedes participantes de Mayo Clinic

Los estatus de los estudios cambian con frecuencia. Comunícate con el equipo del estudio para obtener la información más actualizada acerca de la posibilidad de participar.

Sede de Mayo Clinic Estatus Contacto

Rochester, Minn.

Investigador principal de Mayo Clinic

Melissa Snyder, Ph.D.

Abierto para la inscripción

Contact information:

Melissa Snyder Ph.D.

(507) 284-0031

snyder.melissa@mayo.edu

More information

Publicaciones

Publications are currently not available

Otros temas en investigación

.
CLS-20524162

Mayo Clinic Footer