Ensayos clínicos

Inclusion Criteria:

• Age ≥ 18 years.
• Histological confirmation of melanoma. Patients may have completed biopsy outside of Mayo Clinic, but there must be an internal review done to confirm diagnosis prior to confirming eligibility.
• Measurable or non-measurable disease.  Patient must meet one of these criteria.
• ECOG Performance Status (PS) ≤ 3.
• sPD-L1 levels >1.7 ng/ml.
• Negative pregnancy test done ≤ 7 days prior to radiation therapy, for women of childbearing potential only.
• Provide written informed consent.
• Willing to return to enrolling institution for follow-up (during the Active Monitoring Phase of the study).
• Willing to provide blood samples for correlative research purposes.

Exclusion Criteria:

• Persons taking a biotin supplement.
• sPD-L1 level < 1.7 ng/ml by ELISA.
• Pregnant or nursing women.
• Men or women of childbearing potential who are unwilling to employ adequate contraception.

Eligibility last updated 12/15/21. Questions regarding updates should be directed to the study team contact.