Ensayos clínicos

Inclusion Criteria:

• Must be 18 years old or older.
• Meet diagnosis criteria for POTS = a heart rate increase of ≥ 30bpm with supine to 10 minutes of standing or head-up tilt or heart rate exceeding 120 ppm after 10 minutes of standing or tilt without evidence of orthostaticth POTS ≥ 6 months prior to participation in the study (chronic).
• Those in ET group must be on stable medications for at least 1 month and medication must remain consistent for duration of study participation. For those in the SC group, a change in medication will be allowed within the first month following baseline testing, but then must remain consistent until 3-month testing time point.
• Ehlers-Danlos Syndrome (EDS) patients will be included, but will target equal randomization between treatment groups.

Exclusion Criteria:

• Female subjects must not be pregnant or trying to become pregnant during duration of study participation
• Individual is not eligible if they are currently exercising, cut off >30 minutes of structured exercise/physical activity per week. (assessed by Global Physical Activity Questionnaire)