Ensayos clínicos

Inclusion Criteria:

• Adults with obesity (BMI > 30Kg/m^2); these will be otherwise healthy individuals with no unstable psychiatric disease and controlled comorbidities or other diseases.
• Age: 18-75 years old.
• Gender: Men or women. Women of childbearing potential will have negative pregnancy tests within 48 hours of enrollment.
• Women of childbearing potential must agree to use a method of effective contraception during study participation.
• Subject must have an Apple iPhone 6s or later with iOS 13 or later and be willing to download the VitalCare (VitalTech Affiliates LLC) application from the Apple App Store.
• Able to provide written informed consent prior to any study procedures, and be willing and able to comply with study procedures.

Exclusion Criteria:

• History of Abdominal bariatric surgery.
• Weight is greater than 450 lbs. (204 kg).
• Recent use (within the last three months) of any antiobesity medication.
• Recent weight change (gain or loss weight greater than 3% TBW in the last 3 months).
• Positive history of chronic gastrointestinal diseases, or systemic disease that could affect gastrointestinal motility, or use of medications that may alter gastrointestinal motility, appetite or absorption; e.g., orlistat, within the last 6 months.
• Significant untreated psychiatric dysfunction based upon screening with the Hospital Anxiety and Depression Inventory (HAD), and the Questionnaire on Eating and Weight Patterns (binge eating disorders and bulimia). If such a dysfunction is identified by an anxiety or depression score > 11 or difficulties with substance or eating disorders, the participant will be excluded and given a referral letter to his/her primary care doctor for further appraisal and follow-up.
• Hypersensitivity or contraindication to the study medication.
• Participant unable or unwilling to follow protocol including use of the wearable activity tracker, digital wellness devices, VitalCare application, or unwilling to sign consent.
• Principal Investigator discretion.