Ensayos clínicos

Inclusion Criteria

All participants in the study must meet all of the following inclusion criteria to participate in this study:

• Diagnosed with chronic rhinosinusitis who have undergone previous functional endoscopic sinus surgery including at minimum maxillary antrostomy and anterior ethmoidectomy.
• Active mucopurulence on endoscopic examination with corresponding culture demonstrating pathogenic bacterial growth.
• Completion of written informed consent.
• No prior enrollment into this study.
• Refractory to maximal medical therapy.

Exclusion Criteria:

Candidates meeting any of the following exclusion criteria at baseline will be excluded from study participation:

• Patient has not had prior endoscopic sinus surgery consisting of at minimum bilateral maxillary antrostomy and anterior ethmoidectomy.
• Patient is currently being treated with oral antibiotics.
• Patient has been treated with oral or topical antibiotics within the past 14 days.
• Participation in an investigational drug study simultaneously with participation in this study.
• Concurrent use of oral steroids.
• Known to currently be pregnant.