Ensayos clínicos

Inclusion Criteria: 

• Willing and able to provide informed consent (age 18+) or parental permission and assent (ages 12-17).
• Age 12 or older.
• Plaque or guttate psoriasis predominantly located on trunk and/or extremities, with a physician global assessment average of > 1.0, and considered a candidate for phototherapy.
• Patient is deemed willing and able to comply with either in-office or in-home phototherapy:
  • In office: Able to travel about 3 times per week for 12 weeks from home, work and/or school during business hours of local site;
  • In home: Has space to accommodate home phototherapy unit and patient (or if 12-17, parent), willing and able to follow home phototherapy instructions.
• New or established patient in the practice.

Exclusion Criteria:

• Patients who are judged unable or unwilling to comply with either in office or in home phototherapy due to time, work, school, or other financial constraints.
• Patients judged unable to follow home phototherapy protocol due to failure to demonstrate understanding of the following: 
  • How to operate the phototherapy device;
  • How to follow the dosing protocol;
  • Requirement to wear protective eyewear and genital protection equipment.
• Patients with known history of lack of efficacy to phototherapy or treated with phototherapy 14 days prior to baseline visit.
• Psoriasis predominantly located on scalp, body folds, genitals, palms and/or soles or with a physician global assessment average of ≤ 1.0.
• Patients deemed unsafe to be treated with phototherapy: 
  • History of photosensitivity or autoimmune disease such as lupus or dermatomyositis which can be aggravated by ultraviolet radiation;
  • History of arsenic intake;
  • Unable to tolerate standing for required duration of treatment due to age or physical function;
  • History of melanoma or multiple non-melanoma skin cancers that in the opinion of the principal investigator contraindicates treatment with phototherapy.
• Clinical site deems the participant is ineligible for reason other than eligibility or screening criteria.