A Study to Evaluate the Characteristics and Role of Mucosal Microbiome after Treatment of Clostridium-difficile Infection

Overview

Información sobre este estudio

The purpose of this study is to characterize the mucosal microbiome in patients who have recently been treated for Clostridium-difficile Infection (CDI) in comparison to that of control population to determine the effect of the mucosal associated microbiome on outcome of CDI.

 

Elegibilidad para la participación

Los requisitos de elegibilidad de los participantes incluyen la edad, el sexo, el tipo y el estadio de la enfermedad, y los problemas de salud o tratamientos previos. Las pautas difieren de un estudio a otro e identifican quiénes pueden o no pueden participar. No hay garantía de que cada persona elegible que desee participar en un ensayo se inscribirá. Comunícate con el equipo del estudio para analizar la elegibilidad del estudio y la posible participación.

Inclusion Criteria - CDI patients:

  • Adults aged 18 and over
  • Confirmed C. difficile infection based on positive C. difficile toxin PCR testing and clinical evidence of diarrhea who are currently undergoing treatment or have completed treatment within the last 6 months

Exclusion Criteria - CDI patients:

  • Known active pregnancy.
  • Other known active gastrointestinal infectious process.
  • Vulnerable adults.
  • Any other disease(s), condition(s) or habit(s) that would interfere with completion of study, or in the judgment of the investigator would potentially interfere with compliance to this study or would adversely affect study outcomes.

Patient Inclusion Criteria - Control Population:

  • Adults aged 18 and over.
  • Undergoing clinically indicated colonoscopy for colon cancer screening or colon polyp surveillance purposes in the absence of active GI symptoms.

Patient Exclusion Criteria - Control Population:

  • Known active pregnancy.
  • Prior diagnosis of CDI.
  • Other known active gastrointestinal infectious process.
  • Vulnerable adults.
  • Any other disease(s), condition(s) or habit(s) that would interfere with completion of study, or in the judgment of the investigator would potentially interfere with compliance to this study or would adversely affect study outcomes.

Sedes participantes de Mayo Clinic

Los estatus de los estudios cambian con frecuencia. Comunícate con el equipo del estudio para obtener la información más actualizada acerca de la posibilidad de participar.

Sede de Mayo Clinic Estatus Contacto

Rochester, Minn.

Investigador principal de Mayo Clinic

Purna Kashyap, M.B.B.S.

Cerrado para la inscripción

Contact information:

Heather Lekatz CCRP

(507)538-1206

Lekatz.Heather@mayo.edu

More information

Publicaciones

Publications are currently not available
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CLS-20467388

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