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Exercise to Treat Frailty in Kidney Transplant Candidates

Overview

Información sobre este estudio

Frailty is a condition characterized by slowness, weakness, low physical activity, wasting, and exhaustion. Frailty increases the risk for adverse outcomes following transplant such as increased length of stay in the hospital, mortality, or graft function. No interventions for frailty are known for patients with renal disease, but exercise programs like pulmonary rehabilitation have been effective in improving frailty in patients with other diseases, such as lung disease. The goal of this study is to test whether exercise will also improve frailty among patients who are waiting for a kidney transplant and who are considered frail or pre-frail.

Elegibilidad para la participación

Los requisitos de elegibilidad de los participantes incluyen la edad, el sexo, el tipo y el estadio de la enfermedad, y los problemas de salud o tratamientos previos. Las pautas difieren de un estudio a otro e identifican quiénes pueden o no pueden participar. No hay garantía de que cada persona elegible que desee participar en un ensayo se inscribirá. Comunícate con el equipo del estudio para analizar la elegibilidad del estudio y la posible participación.

Inclusion Criteria:

  • Aged 18 years or older.
  • Consenting to research.
  • Varying level of kidney function
  • An SPPB score ≤ 10 or considered frail or pre-frail by frailty phenotype (FP).

Exclusion Criteria:

  • Younger than 18 years of age.
  • Patients listed for heart or lung transplants.
  • Terminal illness with a prognosis of less than 6 months.
  • Significant comorbidities that limit rehabilitation potential including pulmonary disease requiring continuous oxygen supplementation, active angina, critical aortic sclerosis, decompensated heart failure, or known ventricular arrhythmia.
  • Kidney transplant candidates without cardiac clearance for transplant.
  • An SPPB score > 10 or not considered frail or pre-frail by FP.
  • Non-English speaker without availability of adequate interpreter services (safety concern).
  • Failure to pass submaximal exercise test.

Sedes participantes de Mayo Clinic

Los estatus de los estudios cambian con frecuencia. Comunícate con el equipo del estudio para obtener la información más actualizada acerca de la posibilidad de participar.

Sede de Mayo Clinic Estatus Contacto

Rochester, Minn.

Investigador principal de Mayo Clinic

Cassie Kennedy, M.D.

Cerrado para la inscripción

Contact information:

Renee Weatherly

(507)284-4862

weatherly.renee@mayo.edu

More information

Publicaciones

Publications are currently not available

Otros temas en investigación

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CLS-20421995

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