Ensayos clínicos

Inclusion Criteria:

• Patient is ≥ 18 years of age.
• LVEF 35%-50%.
• NYHA class I-II.
• QRS duration of ≥ 120 ms.
• Left bundle branch block (LBBB).
• Patient is able to receive a transvenous pectoral CRT implant.
• Patient is able to sign informed consent.
• Two echocardiograms are required to confirm LVEF ≤ 50% (one echo must be within 12 months of enrollment).
• Patient is on optimal and stable medical therapy (ACE inhibitor or AT1 blocker, beta blocker, etc. over the last 6 months).

Exclusion Criteria:

• Advanced comorbid conditions with life expectancy <1 year.
• Patient is < 18 of years of age.
• Patient has a CRT device.
• Female patients who is pregnant or not on a reliable form of birth control. Women of childbearing potential are required to have negative pregnancy test within the 7 days prior to device implant.
• Unwilling or unable to return for required follow-up visits.
• Patient decides study participation is cost-prohibited.