Ensayos clínicos

INCLUSION CRITERIA - Case Tissue:

• Patient has a histological diagnosis of primary clear cell RCC, papillary cell RCC, chromophobe RCC, oncocytoma, or urothelial cell carcinoma.
• Age > 18 years old.

EXCLUSION CRITERIA - Case Tissue:

• Patient has von Hippel-Lindau disease (VHL), Hereditary leiomyomatosis and renal cell cancer (HLRCC), Hereditary papillary renal carcinoma (HPRC), or Birt-Hogg-Dubé syndrome (BHD).
• The current target pathology is a recurrence.
• Patient has undergone any prior radiation therapy to target lesion prior to surgery.
• Patient has received chemotherapy class drugsin the 5 years prior to surgery.
• Patient has had any transplants prior to surgery.
• Patient has confirmation of Lynch Syndrome, is presumed to have Lynch Syndrome, or has familial cancer syndrome X.
• Patient has Neuphritis (Glomerulus or Interstitial), Poly Cystic Kidney Disease, Glomerulonephropathies or Acquired Renal Kidney Disease.

EXCLUSION CRITERIA - Renal Control Tissue:

• Patient has von Hippel-Lindau disease (VHL), Hereditary leiomyomatosis and renal cell cancer (HLRCC), Hereditary papillary renal carcinoma (HPRC), or Birt-Hogg-Dubé syndrome (BHD).
• Patient has inflammation, atypia, or hyperplasia of the parenchyma.
• Patient has a current or past history of renal cancer.
• Patient has undergone any prior radiation therapy to target lesion prior to surgery.
• Patient has received chemotherapy class drugs in the 5 years prior to surgery.
• Patient has had any transplants prior to surgery.
• Patient has confirmation of Lynch Syndrome, is presumed to have Lynch Syndrome, or has familial cancer syndrome X.
• Patient has Neuphritis (Glomerulus or Interstitial), Poly Cystic Kidney Disease, Glomerulonephropathies or Acquired Renal Kidney Disease.

EXCLUSION CRITERIA - Urothelial Control Tissue:

• Patient has von Hippel-Lindau disease (VHL), Hereditary leiomyomatosis and renal cell cancer (HLRCC), Hereditary papillary renal carcinoma (HPRC), or Birt-Hogg-Dubé syndrome (BHD).
• Patient has inflammation, atypia, or hyperplasia of the urothelium.
• Patient has a current or past history of urothelial cancer.
• Patient has undergone any prior radiation therapy to target lesion prior to surgery.
• Patient has received chemotherapy class drugs in the 5 years prior to surgery.
• Patient has had any transplants prior to surgery.

INCLUSION CRITERIA - Case Bloods and Urine:

• Patient has a histological diagnosis of primary clear cell RCC, papillary cell RCC, chromophobe RCC, oncocytoma, or urothelial cell carcinoma.
• Age > 18 years old.

EXCLUSION CRITERIA - Case Bloods and Urine:

• Patient has known primary cancer outside of the urothelium within the last 5 years prior to plasma and urine collection (not including basal cell or squamous cell skin cancers).
• Current target pathology is a recurrence.
• Patient has undergone prior radiation therapy in the 5 years prior to plasma and urine collection.
• Patient has received chemotherapy class drugs in the 5 years prior to plasma and urine collection.
• Patient has had any transplants prior to plasma and urine collection.
• Patient has von Hippel-Lindau disease (VHL), Hereditary leiomyomatosis and renal cell cancer (HLRCC), Hereditary papillary renal carcinoma (HPRC), or Birt-Hogg-Dubé syndrome (BHD).
• Gross urinary incontinence.
• Patient has undergone cystectomy.