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A Study to Evaluate Magnetic Resonance (MR) to Estimate Liver Fat and Fibrosis Among American Indians with High Rates of Obesity, Insulin Resistance, and Variable Alcohol Use

Overview

Información sobre este estudio

This research study will evaluate magnetic resonance (MR) studies (imaging and elastography) to assess methods to estimate liver fat and fibrosis among American Indians (AI) with high rates of obesity, insulin resistance and variable alcohol (EtOH) use. MR examinations in this study are obtained in the same way as routine images are obtained on MR scanners, using radio waves and magnetic fields.

Elegibilidad para la participación

Los requisitos de elegibilidad de los participantes incluyen la edad, el sexo, el tipo y el estadio de la enfermedad, y los problemas de salud o tratamientos previos. Las pautas difieren de un estudio a otro e identifican quiénes pueden o no pueden participar. No hay garantía de que cada persona elegible que desee participar en un ensayo se inscribirá. Comunícate con el equipo del estudio para analizar la elegibilidad del estudio y la posible participación.

Inclusion Criteria:

  1. The potential participant previously participated in the Strong Heart Study (SHS).
  2. The potential participant is between 25 and 70 years of age.
  3. Potential participant is willing and able to complete all procedures and observations specified in the protocol.
  4. The potential participant has been fully informed and has personally signed and dated the written Informed Consent and Health Insurance Portability and Accountability Act (HIPAA) documents.

Exclusion Criteria:

  1. The potential participant has any contraindication to MR imaging, such as participants with pacemakers, metallic cardiac valves, magnetic material such as surgical clips, implanted electronic infusion pumps or other conditions that would preclude proximity to a strong magnetic field.
  2. The potential participant has a history claustrophobia.
  3. The potential participant is a female who is pregnant.
  4. The potential participant has alternative causes of liver disease (e.g. viral hepatitis, genetic or autoimmune liver diseases, or diseases that might alter study findings).
  5. The potential participant exceeds the imaging center’s weight limit.

Sedes participantes de Mayo Clinic

Los estatus de los estudios cambian con frecuencia. Comunícate con el equipo del estudio para obtener la información más actualizada acerca de la posibilidad de participar.

Sede de Mayo Clinic Estatus

Scottsdale/Phoenix, Ariz.

Investigador principal de Mayo Clinic

Alvin Silva, M.D.

Cerrado para la inscripción

More information

Publicaciones

Publications are currently not available

Otros temas en investigación

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CLS-20336664

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