A Databank Study of Molecular Circulatory Biomarkers in Non-localized Renal and Testicular Cancer Patients

Overview

Información sobre este estudio

The purpose of this study is to collect blood and urine specimens from cancer patients with non-localized kidney cancer receiving therapeutic interventions and patients with a diagnosis of testicular cancer. To clinically annotate a registry in the patients enrolled for the purpose of developing new cancer related molecular biomarkers for prognosis and prediction of clinical outcomes. This will include proteomic, genomic and metabolomic based molecular profiling in blood and urine specimens collected from cancer patients.

Elegibilidad para la participación

Los requisitos de elegibilidad de los participantes incluyen la edad, el sexo, el tipo y el estadio de la enfermedad, y los problemas de salud o tratamientos previos. Las pautas difieren de un estudio a otro e identifican quiénes pueden o no pueden participar. No hay garantía de que cada persona elegible que desee participar en un ensayo se inscribirá. Comunícate con el equipo del estudio para analizar la elegibilidad del estudio y la posible participación.

Inclusion Criteria:    

  1. Subjects with a histological confirmed diagnosis of testicular cancer who are destined to initiate standard of care therapeutic interventions. This includes testicular cancer subjects with evidence of clinically or biochemically progressive disease post surgical or radiation treatments for localized stage disease as deemed by the treating physician. Biochemical evidence of progressive disease is defined as a serially rising serum tumor marker (AFP-Alpha Feto-Protein; B-HCG-beta human chorionic gonadotropin or LDH). 
  2. Subjects with non-localized kidney cancer being followed or treated at Mayo Clinic as part of standard clinical care.
  3. Age: 18 to 100 years
  4. Subject must be able to sign an informed consent. Informed consent must be signed at the time of enrollment and/or collection of any specimen and/or clinical data (other than PHI needed to screen and identify patients, which will be promptly discarded in a secure fashion if patient is not enrolled on study).

Exclusion Criteria:   

  1. Subjects either incarcerated or with limited decision making capacity.
  2. Subjects clinically judged to be at increased risk of bleeding from phlebotomy.
  3. Subjects with hemoglobin
  4. Subjects with a previous history of known second non-GU malignancy in the past five years.

Sedes participantes de Mayo Clinic

Los estatus de los estudios cambian con frecuencia. Comunícate con el equipo del estudio para obtener la información más actualizada acerca de la posibilidad de participar.

Sede de Mayo Clinic Estatus Contacto

Rochester, Minn.

Investigador principal de Mayo Clinic

Brian Costello, M.D.

Cerrado para la inscripción

Contact information:

Cancer Center Clinical Trials Referral Office

(855) 776-0015

Jacksonville, Fla.

Investigador principal de Mayo Clinic

Winston Tan, M.D.

Cerrado para la inscripción

Contact information:

Cancer Center Clinical Trials Referral Office

(855) 776-0015

More information

Publicaciones

Publications are currently not available
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CLS-20312921

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