Los requisitos de elegibilidad de los participantes incluyen la edad, el sexo, el tipo y el estadio de la enfermedad, y los problemas de salud o tratamientos previos. Las pautas difieren de un estudio a otro e identifican quiénes pueden o no pueden participar. No hay garantía de que cada persona elegible que desee participar en un ensayo se inscribirá. Comunícate con el equipo del estudio para analizar la elegibilidad del estudio y la posible participación.
Inclusion Criteria
Age ≥18 years, male or female
For the Colon cancer subjects: Diagnosis of stage 3 colon cancer without IBD before treatment, during treatment with 5-FU based chemotherapy and post treatment.
Normal colon participants : Normal colonoscopy without current adenomatous polyps, IBD, critical illness, obesity, celiac disease, NASH, IBS, food allergy, malnutrition or current history of diarrhea.
Polyp participants; participants with advanced adenoma (> 1cm in size; villous histology and/or high grade dysplasia without IBD
Active Chronic ulcerative colitis: participants with active CUC.
Carcinoid syndrome: participants with carcinoid syndrome.
Can swallow the mannitol capsule and drink up to 200 ml of water (or approximately 8 cups) and agrees to undergo urine testing up to 3 times during the study.
Exclusion Criteria
Participants with prior GI tract surgical (small or large bowel) resections
For normal colon participants: no h/o IBD critical illness, obesity, celiac disease, NASH, IBS, food allergy, malnutrition or current history of diarrhea.
Women who are pregnant or breast-feeding