Ensayos clínicos

Inclusion Criteria  

Subjects ≥ 18 years of age:

• Age 18+ years
• Able to give informed consent
• Undergoing elective treatment for a solid renal/bladder tumor:
  • Partial nephrectomy/cystectomy
  • Radical nephrectomy/cystectomy
  • Nephrectomy + tumor thrombectomy
  • Cytoreductive nephrectomy +/- metastasectomy for metastatic RCC
  • Radiofrequency ablation or cryotherapy
  • Transurethral resection
  • Metastasectomy for mUC

Subjects < 18 years of age:

• Age 0-17 years
• Parent/Guardian able to give informed consent, and subject able to give assent (ages 7-17)
• Undergoing elective treatment for genitourinary mass, and/or metastases from primary genitourinary tumor, and/or recurrence of genitourinary malignancy, any location, with tissue being obtained via:
  • Nephrectomy
  • Partial nephrectomy
  • Open biopsy
  • Percutaneous biopsy
  • Resection of mass

Exclusion Criteria

Subjects ≥ 18 years of age:

• Bilateral tumors
• Salvage procedure (i.e. treatment for a recurrent tumor)
• Immunosuppressed patient (Use of immunosuppressive medications in past 90 days (Examples include: oral or IV corticosteroids (topical creams or nasal sprays are OK), anti-metabolites (ex. azathioprine, methotrexate), biologics (ex. infliximab), chemotherapy) or imunosuppressive condition (ex. transplant, immunodeficiency syndromes, HIV/AIDS)
• Auto-immune disease (ex. lupus, rheumatoid arthritis, inflammatory bowel disease, etc.)
• Pregnancy

Subjects < 18 years of age:

• Metastases to kidney from non-renal primary
• Auto-immune disease (ex. lupus, rheumatoid arthritis, inflammatory bowel disease, etc.)
• Pregnancy