Ensayos clínicos

Inclusion Criteria

• Normal Subjects
  • Age ≥ 18 years
  • Normal heart sounds
  • Normal breath sounds
  • Measured systolic blood pressure < 140 mm Hg
  • Measured diastolic blood pressure < 90 mm Hg
• Cardiac Amyloidosis
  • Tissue diagnosis of amyloidosis and left ventricular maximal wall thickness > 12 mm by echocardiography or MRI

Exclusion Criteria

• Normal Subjects
  • History of angina, coronary artery disease, heart failure, hypertension, hypertensive medication, valvular heart disease, congenital heart disease, diabetes 
  • Contraindications or relative contraindications to MRI scanning, namely internal defibrillators or pacemakers, cerebral aneurysm clips, severe claustrophobia, and pregnancy or suspected pregnancy (self-reported)
• Cardiac Amyloidosis
  • Contraindications or relative contraindications to MRI scanning (same as with normal subjects)