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A Study of the Relationship between Recruitment Maneuvers and Blood Volume Status in Critically Ill Patients

Overview

Información sobre este estudio

The purpose of this pilot study is to see if recruitment maneuvers performed during ICU care in patients who have a breathing tube are useful in assessing a blood volume status based on changes in their blood pressure during the recruitment maneuver. The recruitment maneuver consists of increasing the pressure of the breath given through the breathing tube, and is commonly done as a standard part of ICU care for patients who are connected to a machine that helps them breathe. Results will be compared to ultrasound measurements of the main vein of the body (inferior vena cava) which serve as a non-invasive standard of care technique.

Elegibilidad para la participación

Los requisitos de elegibilidad de los participantes incluyen la edad, el sexo, el tipo y el estadio de la enfermedad, y los problemas de salud o tratamientos previos. Las pautas difieren de un estudio a otro e identifican quiénes pueden o no pueden participar. No hay garantía de que cada persona elegible que desee participar en un ensayo se inscribirá. Comunícate con el equipo del estudio para analizar la elegibilidad del estudio y la posible participación.

Inclusion Criteria:

  1. Mechanically-ventilated patients admitted to the trauma-surgical ICU (Mary Brigh 7 B/G)  with a clinical diagnosis of hypovolemic or distributive shock, who are undergoing active resuscitation by the ICU team members,
  2. Blood pressure monitoring via arterial line
  3. Arterial line systolic blood pressure ≥90
  4. Age ≥ 18

Exclusion Criteria: 

  1. Patients who are not mechanically ventilated
  2. Patients who do not have an arterial line at time of enrollment
  3. Patients with abdominal dressings which prevent the use of ultrasonography in the epigastrium
  4. Pregnant patients
  5. Patients <18 years of age
  6. Prisoners/Incarcerated individuals
  7. Recent pneumonectomy
  8. Occult pneumothorax (i.e. pneumothorax only visible on chest CT without clinical symptoms)
  9. Patients with angulated, displaced rib fractures with associated pneumothorax and no thoracostomy tube in place at the time of enrollment.
  10. Patients with difficult to control elevated intracranial pressure
  11. Patients with history of emphysematous bleb and spontaneous pneumothorax.
  12. Patients with a tube thoracostomy and active air leak.
  13. Recently placed internal mammary grafts.

Sedes participantes de Mayo Clinic

Los estatus de los estudios cambian con frecuencia. Comunícate con el equipo del estudio para obtener la información más actualizada acerca de la posibilidad de participar.

Sede de Mayo Clinic Estatus

Rochester, Minn.

Investigador principal de Mayo Clinic

Erica Loomis, M.D.

Cerrado para la inscripción

More information

Publicaciones

Publications are currently not available

Otros temas en investigación

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CLS-20197672

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