Ensayos clínicos

Inclusion Criteria: - Patients with squamous cell carcinoma, depth of invasion > 1 mm - Patients with T1 or T2 tumors (International Federation of Gynecology and Obstetrics[FIGO] staging), tumors < 4 cm, and/or not encroaching in urethra, vagina, or anus with clinically negative inguinofemoral lymph nodes - Localization and size of the tumor are such that perilesional injection of the tracers at three or four sites is possible - Preoperative imaging do not show enlarged (< 1.5 cm) suspicious nodes - No inoperable tumors and tumors with diameter > 4 cm - No patients with inguinofemoral lymph nodes, at palpation clinically suspect for metastases, at radiology enlarged (> 1.5 cm)/suspicious groin nodes, and with cytologically proven inguinofemoral lymph node metastases - No patients with multifocal tumors - No concurrent intensity-modulated radiation therapy - Patients who are currently on an investigational drug for the treatment of vulvar cancer are excluded from participation in this trial