Publications

  1. Ashrafzadeh-Kian S, Figdore D, Larson B, Deters R, Abou-Diwan C, Bornhorst J, Algeciras-Schimnich A. Head-to-head comparison of four plasma neurofilament light chain (NfL) immunoassays. Clin Chim Acta. 2024 Jun 13; 561:119817 Epub 2024 June 13
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  2. Schindler SE, Galasko D, Pereira AC, Rabinovici GD, Salloway S, Suarez-Calvet M, Khachaturian AS, Mielke MM, Udeh-Momoh C, Weiss J, Batrla R, Bozeat S, Dwyer JR, Holzapfel D, Jones DR, Murray JF, Partrick KA, Scholler E, Vradenburg G, Young D, Algeciras-Schimnich A, Aubrecht J, Braunstein JB, Hendrix J, Hu YH, Mattke S, Monane M, Reilly D, Somers E, Teunissen CE, Shobin E, Vanderstichele H, Weiner MW, Wilson D, Hansson O. Acceptable performance of blood biomarker tests of amyloid pathology - recommendations from the Global CEO Initiative on Alzheimer's Disease. Nat Rev Neurol. 2024 Jun 12 Epub 2024 June 12
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  3. Bornhorst JA, Algeciras-Schimnich A. Proteomic Identification of Plasma Proteins Associated with Future Dementia Development. Clin Chem. 2024 May 14 [Epub ahead of print]
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  4. Diaz-Galvan P, Przybelski SA, Algeciras-Schimnich A, Figdore DJ, Lesnick TG, Schwarz CG, Senjem ML, Gunter JL, Jack CR Jr, Min PH, Jain MK, Miyagawa T, Forsberg LK, Fields JA, Savica R, Graff-Radford J, Ramanan VK, Jones DT, Botha H, St Louis EK, Knopman DS, Graff-Radford NR, Ferman TJ, Petersen RC, Lowe VJ, Boeve BF, Kantarci K. Plasma biomarkers of Alzheimer's disease in the continuum of dementia with Lewy bodies. Alzheimers Dement. 2024 Apr; 20 (4):2485-2496 Epub 2024 Feb 08
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  5. Hoong CWS, Sfeir J, Algeciras-Schimnich A, Clarke BL. A retrospective cohort of tumor-induced osteomalacia and case series of malignant disease. J Clin Endocrinol Metab. 2024 Mar 20 [Epub ahead of print]
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  6. Jack CR Jr, Wiste HJ, Algeciras-Schimnich A, Weigand SD, Figdore DJ, Lowe VJ, Vemuri P, Graff-Radford J, Ramanan VK, Knopman DS, Mielke MM, Machulda MM, Fields J, Schwarz CG, Cogswell PM, Senjem ML, Therneau TM, Petersen RC. Comparison of plasma biomarkers and amyloid PET for predicting memory decline in cognitively unimpaired individuals. Alzheimers Dement. 2024 Mar; 20 (3):2143-2154 Epub 2024 Jan 24
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  7. Cogswell PM, Lundt ES, Therneau TM, Wiste HJ, Graff-Radford J, Algeciras-Schimnich A, Lowe VJ, Mielke MM, Schwarz CG, Senjem ML, Gunter JL, Knopman DS, Vemuri P, Petersen RC, Jack CR Jr. Modeling the temporal evolution of plasma p-tau in relation to amyloid beta and tau PET. Alzheimers Dement. 2024 Feb; 20 (2):1225-1238 Epub 2023 Nov 14
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  8. Raghavan S, Przybelski SA, Lesnick TG, Fought AJ, Reid RI, Gebre RK, Windham BG, Algeciras-Schimnich A, Machulda MM, Vassilaki M, Knopman DS, Jack CR Jr, Petersen RC, Graff-Radford J, Vemuri P. Vascular risk, gait, behavioral, and plasma indicators of VCID. Alzheimers Dement. 2024 Feb; 20 (2):1201-1213 Epub 2023 Nov 06
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  9. Figdore DJ, Wiste HJ, Bornhorst JA, Bateman RJ, Li Y, Graff-Radford J, Knopman DS, Vemuri P, Lowe VJ, Jr CRJ, Petersen RC, Algeciras-Schimnich A. Performance of the Lumipulse plasma Abeta42/40 and pTau181 immunoassays in the detection of amyloid pathology. Alzheimers Dement (Amst). 2024 Jan-Mar; 16 (1):e12545 Epub 2024 Jan 31
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  10. Ramanan VK, Gebre RK, Graff-Radford J, Hofrenning E, Algeciras-Schimnich A, Figdore DJ, Lowe VJ, Mielke MM, Knopman DS, Ross OA, Jack CR Jr, Petersen RC, Vemuri P. Genetic risk scores enhance the diagnostic value of plasma biomarkers of brain amyloidosis. Brain. 2023 Nov 2; 146 (11):4508-4519
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  11. Galior KD, Ladwig PM, Snyder MR, Algeciras-Schimnich A, Bornhorst JA, Block DR, Baumann NA, Willrich MAV. Lack of observed interference by therapeutic monoclonal antibodies in select commonly utilized immunoassays. Clin Biochem. 2023 Nov; 121-122:110685 Epub 2023 Nov 14
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  12. Mielke MM, Dage JL, Frank RD, Algeciras-Schimnich A, Knopman DS, Lowe VJ, Bu G, Vemuri P, Graff-Radford J, Jack CR Jr, Petersen RC. Author Correction: Performance of plasma phosphorylated tau 181 and 217 in the community. Nat Med. 2023 Nov; 29 (11):2954
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  13. Ramanan VK, Graff-Radford J, Syrjanen J, Shir D, Algeciras-Schimnich A, Lucas J, Martens YA, Carrasquillo MM, Day GS, Ertekin-Taner N, Lachner C, Willis FB, Knopman DS, Jack CR Jr, Petersen RC, Vemuri P, Graff-Radford N, Mielke MM. Association of Plasma Biomarkers of Alzheimer Disease With Cognition and Medical Comorbidities in a Biracial Cohort. Neurology. 2023 Oct 3; 101 (14):e1402-e1411 Epub 2023 Aug 14
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  14. Giovanella L, D'Aurizio F, Algeciras-Schimnich A, Gorges R, Petranovic Ovcaricek P, Tuttle RM, Visser WE, Verburg FA, hsTg&TgAb Consensus Working Group. Thyroglobulin and thyroglobulin antibody: an updated clinical and laboratory expert consensus. Eur J Endocrinol. 2023 Aug 2; 189 (2):R11-R27
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  15. Ashrafzadeh-Kian SL, Ito N, Srivastava T, Garg U, Kato H, Algeciras-Schimnich A, Bornhorst JA. The effect of burosumab on intact and C-terminal FGF23 measurements. Clin Endocrinol (Oxf). 2023 Aug; 99(2):152-157. Epub 2022 Oct 31.
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  16. Krell-Roesch J, Zaniletti I, Syrjanen JA, Kremers WK, Algeciras-Schimnich A, Dage JL, van Harten AC, Fields JA, Knopman DS, Jack CR Jr, Petersen RC, Vassilaki M, Geda YE. Plasma-derived biomarkers of Alzheimer's disease and neuropsychiatric symptoms: A community-based study. Alzheimers Dement (Amst). 2023 Jul-Sep; 15 (3):e12461 Epub 2023 July 30
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  17. Bermudez C, Graff-Radford J, Syrjanen JA, Stricker NH, Algeciras-Schimnich A, Kouri N, Kremers WK, Petersen RC, Jack CR Jr, Knopman DS, Dickson DW, Nguyen AT, Reichard RR, Murray ME, Mielke MM, Vemuri P. Plasma biomarkers for prediction of Alzheimer's disease neuropathologic change. Acta Neuropathol. 2023 Jul; 146 (1):13-29 Epub 2023 June 03
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  18. Bornhorst JA, Figdore D, Campbell MR, Pazdernik VK, Mielke MM, Petersen RC, Algeciras-Schimnich A. Corrigendum to "Plasma neurofilament light chain (NfL) reference interval determination in an age-stratified cognitively unimpaired cohort" [Clin. Chim. Acta 535 (2022) 153-156]. Clin Chim Acta. 2023 Jun 1; 546:117396 Epub 2023 May 25
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  19. Jack CR, Wiste HJ, Algeciras-Schimnich A, Figdore DJ, Schwarz CG, Lowe VJ, Ramanan VK, Vemuri P, Mielke MM, Knopman DS, Graff-Radford J, Boeve BF, Kantarci K, Cogswell PM, Senjem ML, Gunter JL, Therneau TM, Petersen RC. Predicting amyloid PET and tau PET stages with plasma biomarkers. Brain. 2023 May 2; 146 (5):2029-2044
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  20. Maus A, Fatica EM, Taylor R, Larson BJ, Algeciras-Schimnich A, Singh RJ, Grebe SK. Identification, Measurement, and Assessment of the Clinical Utility of Human Pancreatic Polypeptide by Liquid Chromatography-Tandem Mass Spectrometry. J Proteome Res. 2023 Apr 7; 22 (4):1322-1330 Epub 2023 Mar 07
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  21. Ramos P, Larson B, Ashrafzadeh-Kian S, Ito N, Kato H, Bornhorst JA, Algeciras-Schimnich A. Intact Fibroblast Growth Factor 23 Concentrations in Hypophosphatemic Disorders. Endocr Pract. 2023 Mar; 29(3):193-198. Epub 2023 Jan 07.
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  22. Ashcherkin N, Patel AA, Algeciras-Schimnich A, Doshi KB. Bone turnover markers to monitor oral bisphosphonate therapy. Cleve Clin J Med. 2023 Jan 3; 90 (1):26-31 Epub 2023 Jan 03
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  23. Shir D, Mielke MM, Hofrenning EI, Lesnick TG, Knopman DS, Petersen RC, Jack CR, Algeciras-Schimnich A, Vemuri P, Graff-Radford J. Associations of Neurodegeneration Biomarkers in Cerebrospinal Fluid with Markers of Alzheimer's Disease and Vascular Pathology. J Alzheimers Dis. 2023; 92 (3):887-898
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  24. Barbesino G, Algeciras-Schimnich A, Bornhorst J. Thyroglobulin Assay Interferences: Clinical Usefulness of Mass-Spectrometry Methods. J Endocr Soc. 2022 Nov 17; 7 (1):bvac169 Epub 2022 Nov 02
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  25. Maus A, Figdore D, Milosevic D, Algeciras-Schimnich A, Bornhorst J. Comparison of intact protein and digested peptide techniques for high throughput proteotyping of ApoE. Clin Proteomics. 2022 Nov 15; 19 (1):42
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  26. Graff-Radford J, Mielke MM, Hofrenning EI, Kouri N, Lesnick TG, Moloney CM, Rabinstein A, Cabrera-Rodriguez JN, Rothberg DM, Przybelski SA, Petersen RC, Knopman DS, Dickson DW, Jack CR, Algeciras-Schimnich A, Nguyen AT, Murray ME, Vemuri P. Association of plasma biomarkers of amyloid and neurodegeneration with cerebrovascular disease and Alzheimer's disease. Neurobiol Aging. 2022 Nov; 119:1-7 Epub 2022 July 24
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  27. Chang BK, Day GS, Graff-Radford J, McKeon A, Flanagan EP, Algeciras-Schimnich A, Mielke MM, Nguyen A, Jones DT, Toledano M, Kremers WK, Knopman DS, Petersen RC, Li W. Alzheimer's disease cerebrospinal fluid biomarkers differentiate patients with Creutzfeldt-Jakob disease and autoimmune encephalitis. Eur J Neurol. 2022 Oct; 29 (10):2905-2912 Epub 2022 July 05
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  28. Bornhorst JA, Figdore D, Campbell MR, Pazdernik VK, Mielke MM, Petersen RC, Algeciras-Schimnich A. Plasma neurofilament light chain (NfL) reference interval determination in an Age-stratified cognitively unimpaired cohort. Clin Chim Acta. 2022 Oct 01; 535:153-156. Epub 2022 Aug 27.
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  29. Saadeh RS, Ramos PA, Algeciras-Schimnich A, Flanagan EP, Pittock SJ, Willrich MA. An Update on Laboratory-Based Diagnostic Biomarkers for Multiple Sclerosis and Beyond. Clin Chem. 2022 Sep 1; 68 (9):1134-1150
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  30. Byeon SK, Madugundu AK, Garapati K, Ramarajan MG, Saraswat M, Kumar-M P, Hughes T, Shah R, Patnaik MM, Chia N, Ashrafzadeh-Kian S, Yao JD, Pritt BS, Cattaneo R, Salama ME, Zenka RM, Kipp BR, Grebe SKG, Singh RJ, Sadighi Akha AA, Algeciras-Schimnich A, Dasari S, Olson JE, Walsh JR, Venkatakrishnan AJ, Jenkinson G, O'Horo JC, Badley AD, Pandey A. Development of a multiomics model for identification of predictive biomarkers for COVID-19 severity: a retrospective cohort study. Lancet Digit Health. 2022 Sep; 4 (9):e632-e645 Epub 2022 July 11
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  31. Cogswell PM, Wiste HJ, Mielke MM, Schwarz CG, Weigand SD, Lowe VJ, Therneau TM, Knopman DS, Graff-Radford J, Vemuri P, Senjem ML, Gunter JL, Algeciras-Schimnich A, Petersen RC, Jack CR Jr. CSF phosphorylated tau as an indicator of subsequent tau accumulation. Neurobiol Aging. 2022 Sep; 117:189-200 Epub 2022 May 26
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  32. Ashrafzadeh-Kian S, Bornhorst J, Algeciras-Schimnich A. Development of a PTHrP chemiluminescent immunoassay to assess humoral hypercalcemia of malignancy. Clin Biochem. 2022 Jul-Aug; 105-106:75-80 Epub 2022 Apr 14
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  33. Mielke MM, Dage JL, Frank RD, Algeciras-Schimnich A, Knopman DS, Lowe VJ, Bu G, Vemuri P, Graff-Radford J, Jack CR Jr, Petersen RC. Performance of plasma phosphorylated tau 181 and 217 in the community. Nat Med. 2022 Jul; 28 (7):1398-1405 Epub 2022 May 26
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  34. Johnson LM, Genzen JR, Algeciras-Schimnich A, Bornhorst J, Lambert-Messerlian G. PAPP-A Results Cannot Be Used to Accurately Estimate Gestational Age. J Appl Lab Med 2022 Jun 30; 7 (4):1000-1002
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  35. Syrjanen JA, Campbell MR, Algeciras-Schimnich A, Vemuri P, Graff-Radford J, Machulda MM, Bu G, Knopman DS, Jack CR Jr, Petersen RC, Mielke MM. Associations of amyloid and neurodegeneration plasma biomarkers with comorbidities. Alzheimers Dement. 2022 Jun; 18(6):1128-1140. Epub 2021 Sep 27.
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  36. Fatica EM, Larson BJ, Algeciras-Schimnich A, Bornhorst JA. Performance characteristics of the BRAHMS KRYPTOR automated squamous cell carcinoma antigen assay. J Immunol Methods. 2022 May; 504:113257 Epub 2022 Mar 15
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  37. Donegan D, Algeciras-Schimnich A, Ashrafzadeh-Kian S, Erickson D. Insulin-Like Growth Factor 1 in the Early Postoperative Assessment of Acromegaly. Am J Clin Pathol. 2022 Apr 1; 157 (4):595-601
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  38. van Harten AC, Wiste HJ, Weigand SD, Mielke MM, Kremers WK, Eichenlaub U, Dyer RB, Algeciras-Schimnich A, Knopman DS, Jack CR Jr, Petersen RC. Detection of Alzheimer's disease amyloid beta 1-42, p-tau, and t-tau assays. Alzheimers Dement. 2022 Apr; 18 (4):635-644 Epub 2021 July 26
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  39. Mielke MM, Aakre JA, Algeciras-Schimnich A, Proctor NK, Machulda MM, Eichenlaub U, Knopman DS, Vemuri P, Graff-Radford J, Jack CR Jr, Petersen RC, Dage JL. Comparison of CSF phosphorylated tau 181 and 217 for cognitive decline. Alzheimers Dement. 2022 Apr; 18 (4):602-611 Epub 2021 July 26
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  40. Luzzi V, Algeciras-Schimnich A, Calderon B, Colon-Franco JM, Garcia JD, Goldsmith BM, Jara-Aguirre J, Laterza O, Leung-Pineda V, Palavecino EL, Parnas ML, Zabaleta EH, Sierra-Amor R. Impact of the AACC Global Laboratory Quality Initiative in Partnership with Professional Societies and Universities in Latin America and the Caribbean. J Appl Lab Med. 2022 Mar 2; 7 (2):596-606
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  41. Stan MN, Algeciras-Schimnich A, Murthy V, Thapa P, Araki N. Diagnostic Utility of a New Assay for Thyroid Stimulating Immunoglobulins in Graves' Disease and Thyroid Eye Disease. Thyroid. 2022 Feb; 32 (2):170-176 Epub 2021 Dec 31
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  42. Ashrafzadeh-Kian S, Campbell MR, Jara Aguirre JC, Walsh J, Kumanovics A, Jenkinson G, Rinaldo P, Snyder MR, Algeciras-Schimnich A. Role of immune mediators in predicting hospitalization of SARS-CoV-2 positive patients. Cytokine. 2022 Feb; 150:155790. Epub 2021 Dec 25.
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  43. Shir D, Graff-Radford J, Hofrenning EI, Lesnick TG, Przybelski SA, Lowe VJ, Knopman DS, Petersen RC, Jack CR Jr, Vemuri P, Algeciras-Schimnich A, Campbell MR, Stricker NH, Mielke MM. Association of plasma glial fibrillary acidic protein (GFAP) with neuroimaging of Alzheimer's disease and vascular pathology. Alzheimers Dement (Amst). 2022; 14 (1):e12291 Epub 2022 Feb 28
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  44. McCarter SJ, Lesnick TG, Lowe VJ, Rabinstein AA, Przybelski SA, Algeciras-Schimnich A, Ramanan VK, Jack CR, Petersen RC, Knopman DS, Boeve BF, Kantarci K, Vemuri P, Mielke MM, Graff-Radford J. Association Between Plasma Biomarkers of Amyloid, Tau, and Neurodegeneration with Cerebral Microbleeds. J Alzheimers Dis. 2022; 87 (4):1537-1547
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  45. Marks JD, Syrjanen JA, Graff-Radford J, Petersen RC, Machulda MM, Campbell MR, Algeciras-Schimnich A, Lowe V, Knopman DS, Jack CR Jr, Vemuri P, Mielke MM, Alzheimer's Disease Neuroimaging Initiative. Comparison of plasma neurofilament light and total tau as neurodegeneration markers: associations with cognitive and neuroimaging outcomes. Alzheimers Res Ther. 2021 Dec 14; 13 (1):199
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  46. Ryder M, Wentworth M, Algeciras-Schimnich A, Morris JC, Garrity J, Sanders J, Young S, Sanders P, Furmaniak J, Rees Smith B. Blocking the Thyrotropin Receptor with K1-70 in a Patient with Follicular Thyroid Cancer, Graves' Disease, and Graves' Ophthalmopathy. Thyroid. 2021 Oct; 31 (10):1597-1602 Epub 2021 July 08
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  47. Mielke MM, Frank RD, Dage JL, Jeromin A, Ashton NJ, Blennow K, Karikari TK, Vanmechelen E, Zetterberg H, Algeciras-Schimnich A, Knopman DS, Lowe V, Bu G, Vemuri P, Graff-Radford J, Jack CR Jr, Petersen RC. Comparison of Plasma Phosphorylated Tau Species With Amyloid and Tau Positron Emission Tomography, Neurodegeneration, Vascular Pathology, and Cognitive Outcomes. JAMA Neurol. 2021 Sep 1; 78 (9):1108-1117
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  48. Barbesino G, Algeciras-Schimnich A, Bornhorst JA. False Positives in Thyroglobulin Determinations Due to the Presence of Heterophile Antibodies: An Underrecognized and Consequential Clinical Problem. Endocr Pract. 2021 May; 27 (5):396-400 Epub 2021 Feb 11
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  49. Dubey D, Kryzer T, Guo Y, Clarkson B, Cheville JC, Costello BA, Leibovich BC, Algeciras-Schimnich A, Lucchinnetti C, Hammami MB, Knight AM, Howe C, Lennon VA, McKeon A, Pittock SJ. Leucine Zipper 4 Autoantibody: A Novel Germ Cell Tumor and Paraneoplastic Biomarker. Ann Neurol. 2021 May; 89(5):1001-1010. Epub 2021 Feb 28.
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  50. Javorsky BR, Raff H, Carroll TB, Algeciras-Schimnich A, Singh RJ, Colon-Franco JM, Findling JW. New Cutoffs for the Biochemical Diagnosis of Adrenal Insufficiency after ACTH Stimulation using Specific Cortisol Assays. J Endocr Soc. 2021 Apr 1; 5 (4):bvab022 Epub 2021 Feb 18
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  51. Kritmetapak K, Losbanos L, Berent TE, Ashrafzadeh-Kian SL, Algeciras-Schimnich A, Hines JM, Singh RJ, Kumar R. Hyperphosphatemia with elevated serum PTH and FGF23, reduced 1,25(OH)2D and normal FGF7 concentrations characterize patients with CKD. BMC Nephrol. 2021 Mar 30; 22 (1):114
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  52. Campbell MR, Ashrafzadeh S, Petersen RC, Bornhorst JA, Algeciras-Schimnich A. Alzheimer's disease CSF biomarker assays: Impact of methodology changes in clinical practice Alzheimer's Dement. 2021; 17(Suppl. 5):e051426.
  53. Nandakumar V, Bornhorst JA, Algeciras-Schimnich A. Evaluation of Phi Clinical Performance for the Detection of Prostate Cancer in Routine Clinical Practice. Ann Clin Lab Sci. 2021 Jan; 51 (1):3-11
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  54. Campbell MR, Ashrafzadeh-Kian S, Petersen RC, Mielke MM, Syrjanen JA, van Harten AC, Lowe VJ, Jack CR Jr, Bornhorst JA, Algeciras-Schimnich A. P-tau/Abeta42 and Abeta42/40 ratios in CSF are equally predictive of amyloid PET status. Alzheimers Dement (Amst). 2021; 13 (1):e12190 Epub 2021 May 18
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  55. Bornhorst JA, Ramos PA, Sutterer ER, Herrli NM, Figdore DJ, Flieth TL, Ness KM, Fatica EM, Algeciras-Schimnich A. Evaluation of sporadic bovine alkaline phosphatase interference in the Beckman Access unconjugated estriol (uE3) assay affecting maternal serum screening results. Clin Biochem. 2021 Jan; 87:93-99 Epub 2020 Nov 12
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  56. Van Harten AC, Wiste HJ, Weigand SD, Mielke MM, Kremers WK, Eichenlaub U, Batrla-Utermann R, Dyer RB, Algeciras-Schimnich A, Knopman DS, Jack CR Jr, Petersen RC. CSF biomarkers in Olmsted County: Evidence of 2 subclasses and associations with demographics. Neurology. 2020 Jul 21; 95 (3):e256-e267 Epub 2020 June 26
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  57. Nandakumar V, Paul Theobald J, Algeciras-Schimnich A. Evaluation of plasma ACTH stability using the Roche Elecsys immunoassay. Clin Biochem. 2020 Jul; 81:59-62 Epub 2020 Apr 18
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  58. Jara-Aguirre JC, Baumann NA, Block DR, Algeciras-Schimnich A. Human chorionic gonadotropin suspected heterophile interference investigations in immunoassays: a recommended approach. Clin Chem Lab Med. 2019 Jul 26; 57 (8):1192-1196
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  59. Yang JD, Addissie BD, Mara KC, Harmsen WS, Dai J, Zhang N, Wongjarupong N, Ali HM, Ali HA, Hassan FA, Lavu S, Cvinar JL, Giama NH, Moser CD, Miyabe K, Allotey LK, Algeciras-Schimnich A, Theobald JP, Ward MM, Nguyen MH, Befeler AS, Reddy KR, Schwartz M, Harnois DM, Yamada H, Srivastava S, Rinaudo JA, Gores GJ, Feng Z, Marrero JA, Roberts LR. GALAD Score for Hepatocellular Carcinoma Detection in Comparison with Liver Ultrasound and Proposal of GALADUS Score. Cancer Epidemiol Biomarkers Prev. 2019 Mar; 28 (3):531-538 Epub 2018 Nov 21
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  60. Donegan DM, Algeciras-Schimnich A, Hamidi O, Young WF, Nippoldt T, Bancos I, Erickson D. Corticotropin hormone assay interference: A case series. Clin Biochem. 2019 Jan; 63:143-147 Epub 2018 Nov 10
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  61. Kenyon SM, Flieth TL, Algeciras-Schimnich A. Comparing the performance of CA 15-3 CSF to cytology in a cohort of patients with breast cancer leptomeningeal metastasis. Clin Biochem. 2018 Aug; 58:122-124 Epub 2018 June 12
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  62. Colon-Franco JM, Bossuyt PMM, Algeciras-Schimnich A, Bird C, Engstrom-Melnyk J, Fleisher M, Kattan M, Lambert-Messerlian G. Current and Emerging Multianalyte Assays with Algorithmic Analyses-Are Laboratories Ready for Clinical Adoption? Clin Chem 2018 Jun; 64 (6):885-891 Epub 2018 Jan 17
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  63. Algeciras-Schimnich A. Thyroglobulin measurement in the management of patients with differentiated thyroid cancer. Crit Rev Clin Lab Sci. 2018 May; 55 (3):205-218 Epub 2018 Mar 16
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  64. Wongjarupong N, Negron-Ocasio GM, Chaiteerakij R, Addissie BD, Mohamed EA, Mara KC, Harmsen WS, Theobald JP, Peters BE, Balsanek JG, Ward MM, Giama NH, Venkatesh SK, Harnois DM, Charlton MR, Yamada H, Algeciras-Schimnich A, Snyder MR, Therneau TM, Roberts LR. Model combining pre-transplant tumor biomarkers and tumor size shows more utility in predicting hepatocellular carcinoma recurrence and survival than the BALAD models. World J Gastroenterol. 2018 Mar 28; 24 (12):1321-1331
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  65. Cradic KW, Lasho MA, Algeciras-Schimnich A. Validation of the Cut-points Recommended for ROMA Using the Roche Elecsys CA125 and HE4 Assays. Ann Clin Lab Sci. 2018 Jan; 48 (1):90-93
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  66. Grebe SKG, Algeciras-Schimnich A, American Thyroid Association's Laboratory Services Committee, American Association for Clinical Chemistry's Endocrine Division Steering Committee. Laboratory Services for Managing Thyroid Disease: Different and Common Viewpoints of American Thyroid Association Members and of Members of the Endocrine Division of the American Association for Clinical Chemistry. Thyroid 2017 Dec; 27 (12):1583-1585
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  67. Katrangi W, Grebe SKG, Algeciras-Schimnich A. Analytical and clinical performance of thyroglobulin autoantibody assays in thyroid cancer follow-up. Clin Chem Lab Med. 2017 Oct 26; 55 (12):1987-1994
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  68. Kahaly GJ, Algeciras-Schimnich A, Davis TE, Diana T, Feldkamp J, Karger S, Konig J, Lupo MA, Raue F, Ringel MD, Sipos JA, Kratzsch J. United States and European Multicenter Prospective Study for the Analytical Performance and Clinical Validation of a Novel Sensitive Fully Automated Immunoassay for Calcitonin. Clin Chem. 2017 Sep; 63 (9):1489-1496 Epub 2017 July 07
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  69. Katzman BM, Ness KM, Algeciras-Schimnich A. Evaluation of the CLSI EP26-A protocol for detection of reagent lot-to-lot differences. Clin Biochem. 2017 Sep; 50 (13-14):768-771 Epub 2017 Mar 18
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  70. Sturgeon CM, Sprague S, Almond A, Cavalier E, Fraser WD, Algeciras-Schimnich A, Singh R, Souberbielle JC, Vesper HW, IFCC Working Group for PTH. Perspective and priorities for improvement of parathyroid hormone (PTH) measurement - A view from the IFCC Working Group for PTH. Clin Chim Acta. 2017 Apr; 467:42-47.
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  71. Al-Hilli Z, Strajina V, McKenzie TJ, Thompson GB, Farley DR, Regina Castro M, Algeciras-Schimnich A, Richards ML. Thyroglobulin Measurement in Fine-Needle Aspiration Improves the Diagnosis of Cervical Lymph Node Metastases in Papillary Thyroid Carcinoma. Ann Surg Oncol. 2017 Mar; 24 (3):739-744 Epub 2016 Oct 13
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  72. Algeciras-Schimnich A. Commentary. Clin Chem 2016 Oct; 62 (10):1316-7
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  73. Trabuco EC, Moorman PG, Algeciras-Schimnich A, Weaver AL, Cliby WA. Association of Ovary-Sparing Hysterectomy With Ovarian Reserve. Obstet Gynecol. 2016 May; 127 (5):819-827
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  74. Bauer PR, Kashyap R, League SC, Park JG, Block DR, Baumann NA, Algeciras-Schimnich A, Jenkins SM, Smith CY, Gajic O, Abraham RS. Diagnostic accuracy and clinical relevance of an inflammatory biomarker panel for sepsis in adult critically ill patients. Diagn Microbiol Infect Dis. 2016 Feb; 84 (2):175-80 Epub 2015 Oct 09
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  75. Ketha H, Lasho MA, Algeciras-Schimnich A. Analytical and clinical validation of parathyroid hormone (PTH) measurement in fine-needle aspiration biopsy (FNAB) washings. Clin Biochem. 2016 Jan; 49 (1-2):16-21 Epub 2015 Sept 15
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  76. Netzel BC, Grebe SK, Carranza Leon BG, Castro MR, Clark PM, Hoofnagle AN, Spencer CA, Turcu AF, Algeciras-Schimnich A. Thyroglobulin (Tg) Testing Revisited: Tg Assays, TgAb Assays, and Correlation of Results With Clinical Outcomes. J Clin Endocrinol Metab. 2015 Aug; 100 (8):E1074-83 Epub 2015 June 16
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  77. Chaiteerakij R, Zhang X, Addissie BD, Mohamed EA, Harmsen WS, Theobald PJ, Peters BE, Balsanek JG, Ward MM, Giama NH, Moser CD, Oseini AM, Umeda N, Venkatesh S, Harnois DM, Charlton MR, Yamada H, Satomura S, Algeciras-Schimnich A, Snyder MR, Therneau TM, Roberts LR. Combinations of biomarkers and Milan criteria for predicting hepatocellular carcinoma recurrence after liver transplantation. Liver Transpl. 2015 May; 21 (5):599-606
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  78. Akbas N, Schryver PG, Algeciras-Schimnich A, Baumann NA, Block DR, Budd JR, Gaston SJ, Klee GG. Evaluation of Beckman Coulter DxI 800 immunoassay system using clinically oriented performance goals. Clin Biochem. 2014 Nov; 47(16-17):158-63. Epub 2014 Aug 15.
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  79. Donegan D, McIver B, Algeciras-Schimnich A. Clinical consequences of a change in anti-thyroglobulin antibody assays during the follow-up of patients with differentiated thyroid cancer. Endocr Pract. 2014 Oct; 20 (10):1032-6
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  80. Bancos I, Algeciras-Schimnich A, Grebe SK, Donato LJ, Nippoldt TB, Erickson D. Evaluation of Variables Influencing the Measurement of Insulin-like Growth Factor-1. Endocr Pract. 2014 May; 20 (5):421-6
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  81. Bancos I, Algeciras-Schimnich A, Woodmansee WW, Cullinane AK, Donato LJ, Nippoldt TB, Natt N, Erickson D. Determination of nadir growth hormone concentration cutoff in patients with acromegaly. Endocr Pract. 2013 Nov-Dec; 19 (6):937-45
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  82. Tolan NV, Vidal-Folch N, Algeciras-Schimnich A, Singh RJ, Grebe SK. Individualized correction of neuron-specific enolase (NSE) measurement in hemolyzed serum samples. Clin Chim Acta. 2013 Sep 23; 424:216-21. Epub 2013 Jun 15.
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  83. Algeciras-Schimnich A, Bruns DE, Boyd JC, Bryant SC, La Fortune KA, Grebe SK. Failure of current laboratory protocols to detect lot-to-lot reagent differences: findings and possible solutions. Clin Chem. 2013 Aug; 59 (8):1187-94 Epub 2013 Apr 16
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  84. Block DR, Algeciras-Schimnich A. Body fluid analysis: clinical utility and applicability of published studies to guide interpretation of today's laboratory testing in serous fluids. Crit Rev Clin Lab Sci. 2013 Jul-Oct; 50(4-5):107-24.
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  85. Kaleta EJ, Tolan NV, Ness KA, O'Kane D, Algeciras-Schimnich A. CEA, AFP and CA 19-9 analysis in peritoneal fluid to differentiate causes of ascites formation. Clin Biochem. 2013 Jun; 46 (9):814-8 Epub 2013 Feb 27
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  86. Bancos I, Grant CS, Nadeem S, Stan MN, Reading CC, Sebo TJ, Algeciras-Schimnich A, Singh RJ, Dean DS. Risks and benefits of parathyroid fine-needle aspiration with parathyroid hormone washout. Endocr Pract. 2012 Jul-Aug; 18 (4):441-9
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  87. Schnepple DJ, Shepard B, Bren GD, Cummins NW, Natesampillai S, Trushin S, Algeciras-Schimnich A, Meng XW, Sainski AM, Rizza SA, Kaufmann SH, Badley AD. Isolation of a TRAIL antagonist from the serum of HIV-infected patients. J Biol Chem. 2011 Oct 14; 286 (41):35742-35754 Epub 2011 Aug 22
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  88. Algeciras-Schimnich A, Lasho MA, Ness KM, Cheryk LA, Grebe SK. The Roche Elecsys and Siemens-Centaur thyroglobulin autoantibody assays show comparable clinical performance to the recently unavailable Beckman-Coulter access thyroglobulin autoantibody assay in identifying samples with potentially false-low Thyroid. 2011 Jul; 21(7):813-4.
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  89. McDonald JS, Milosevic D, Reddi HV, Grebe SK, Algeciras-Schimnich A. Analysis of circulating microRNA: preanalytical and analytical challenges. Clin Chem. 2011 Jun; 57(6):833-40. Epub 2011 Apr 12.
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  90. Reddi HV, Madde P, Milosevic D, Hackbarth JS, Algeciras-Schimnich A, McIver B, Grebe SK, Eberhardt NL. The Putative PAX8/PPARgamma Fusion Oncoprotein Exhibits Partial Tumor Suppressor Activity through Up-Regulation of Micro-RNA-122 and Dominant-Negative PPARgamma Activity. Genes Cancer. 2011 Jan; 2 (1):46-55
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  91. Hackbarth JS, Murata K, Reilly WM, Algeciras-Schimnich A. Performance of CEA and CA19-9 in identifying pleural effusions caused by specific malignancies. Clin Biochem. 2010 Sep; 43 (13-14):1051-5 Epub 2010 June 08
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  92. Algeciras-Schimnich A, Milosevic D, McIver B, Flynn H, Reddi HV, Eberhardt NL, Grebe SK. Evaluation of the PAX8/PPARG translocation in follicular thyroid cancer with a 4-color reverse-transcription PCR assay and automated high-resolution fragment analysis. Clin Chem. 2010 Mar; 56 (3):391-8 Epub 2010 Jan 07
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  93. Snozek CL, O'Kane DJ, Algeciras-Schimnich A. Pharmacogenetics of solid tumors: directed therapy in breast, lung, and colorectal cancer: a paper from the 2008 william beaumont hospital symposium on molecular pathology. J Mol Diagn. 2009 Sep; 11 (5):381-9 Epub 2009 July 30
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  94. Singh VP, Bren GD, Algeciras-Schimnich A, Schnepple D, Navina S, Rizza SA, Dawra RK, Saluja AK, Chari ST, Vege SS, Badley AD. Nelfinavir/ritonavir reduces acinar injury but not inflammation during mouse caerulein pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2009 May; 296 (5):G1040-6 Epub 2009 Mar 12
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  95. Algeciras-Schimnich A, Preissner CM, Theobald JP, Finseth MS, Grebe SK. Procalcitonin: a marker for the diagnosis and follow-up of patients with medullary thyroid carcinoma. J Clin Endocrinol Metab. 2009 Mar; 94 (3):861-8 Epub 2008 Dec 16
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  96. Algeciras-Schimnich A, O'Kane DJ, Snozek CL. Pharmacogenomics of tamoxifen and irinotecan therapies. Clin Lab Med. 2008 Dec; 28 (4):553-67
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  97. Algeciras-Schimnich A, Preissner CM, Young WF Jr, Singh RJ, Grebe SK. Plasma chromogranin A or urine fractionated metanephrines follow-up testing improves the diagnostic accuracy of plasma fractionated metanephrines for pheochromocytoma. J Clin Endocrinol Metab. 2008 Jan; 93 (1):91-5 Epub 2007 Oct 16
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  98. Algeciras-Schimnich A, Belzacq-Casagrande AS, Bren GD, Nie Z, Taylor JA, Rizza SA, Brenner C, Badley AD. Analysis of HIV Protease Killing Through Caspase 8 Reveals a Novel Interaction Between Caspase 8 and Mitochondria. Open Virol J. 2007 Dec 27; 1:39-46
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  99. Algeciras-Schimnich A, Cook WJ, Milz TC, Saenger AK, Karon BS. Evaluation of hemoglobin interference in capillary heel-stick samples collected for determination of neonatal bilirubin. Clin Biochem. 2007 Nov; 40(16-17):1311-6. Epub 2007 Aug 11.
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  100. Sokolova I, Algeciras-Schimnich A, Song M, Sitailo S, Policht F, Kipp BR, Voss JS, Halling KC, Ruth A, King W, Underwood D, Brainard J, Morrison L. Chromosomal biomarkers for detection of human papillomavirus associated genomic instability in epithelial cells of cervical cytology specimens. J Mol Diagn. 2007 Nov; 9(5):604-11.
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  101. Algeciras-Schimnich A, Policht F, Sitailo S, Song M, Morrison L, Sokolova I. Evaluation of quantity and staining pattern of human papillomavirus (HPV)-infected epithelial cells in thin-layer cervical specimens using optimized HPV-CARD assay. Cancer. 2007 Oct 25; 111(5):330-8.
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  102. Vlahakis SR, Bren GD, Algeciras-Schimnich A, Trushin SA, Schnepple DJ, Badley AD. Flying in the face of resistance: antiviral-independent benefit of HIV protease inhibitors on T-cell survival. Clin Pharmacol Ther. 2007 Sep; 82(3):294-9. Epub 2007 Mar 14.
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  103. Nie Z, Bren GD, Vlahakis SR, Schimnich AA, Brenchley JM, Trushin SA, Warren S, Schnepple DJ, Kovacs CM, Loutfy MR, Douek DC, Badley AD. Human immunodeficiency virus type 1 protease cleaves procaspase 8 in vivo. J Virol. 2007 Jul; 81 (13):6947-56 Epub 2007 Apr 18
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  104. Trushin SA, Algeciras-Schimnich A, Vlahakis SR, Bren GD, Warren S, Schnepple DJ, Badley AD. Glycoprotein 120 binding to CXCR4 causes p38-dependent primary T cell death that is facilitated by, but does not require cell-associated CD4. J Immunol. 2007 Apr 15; 178 (8):4846-53
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  105. Reddi HV, Algeciras-Schimnich A, McIver B, Eberhardt NL, Grebe SKG. Chromosomal rearrangements and the pathogenesis of differentiated thyroid cancer. Onc Rev. 2007; 1(2):81-90.
  106. Barnhart BC, Pietras EM, Algeciras-Schimnich A, Salmena L, Sayama K, Hakem R, Peter ME. CD95 apoptosis resistance in certain cells can be overcome by noncanonical activation of caspase-8. Cell Death Differ. 2005 Jan; 12(1):25-37.
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  107. Zazzeroni F, Papa S, Algeciras-Schimnich A, Alvarez K, Melis T, Bubici C, Majewski N, Hay N, De Smaele E, Peter ME, Franzoso G. Gadd45 beta mediates the protective effects of CD40 costimulation against Fas-induced apoptosis. Blood. 2003 Nov 1; 102(9):3270-9 Epub 2003 Jul 10.
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  108. Algeciras-Schimnich A, Pietras EM, Barnhart BC, Legembre P, Vijayan S, Holbeck SL, Peter ME. Two CD95 tumor classes with different sensitivities to antitumor drugs. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11445-50 Epub 2003 Sep 22.
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  109. Algeciras-Schimnich A, Peter ME. Actin dependent CD95 internalization is specific for type I cells. FEBS Lett. 2003 Jul 10; 546(2-3):185-8.
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  110. Algeciras-Schimnich A, Barnhart BC, Peter ME. Apoptosis-independent functions of killer caspases. Curr Opin Cell Biol. 2002 Dec; 14(6):721-6.
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  111. Algeciras-Schimnich A, Vlahakis SR, Villasis-Keever A, Gomez T, Heppelmann CJ, Bou G, Paya CV. CCR5 mediates Fas- and caspase-8 dependent apoptosis of both uninfected and HIV infected primary human CD4 T cells. AIDS. 2002 Jul 26; 16 (11):1467-78
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  112. Chang DW, Xing Z, Pan Y, Algeciras-Schimnich A, Barnhart BC, Yaish-Ohad S, Peter ME, Yang X. c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. EMBO J. 2002 Jul 15; 21(14):3704-14.
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  113. Stegh AH, Barnhart BC, Volkland J, Algeciras-Schimnich A, Ke N, Reed JC, Peter ME. Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator protein. J Biol Chem. 2002 Feb 8; 277(6):4351-60. Epub 2001 Dec 03.
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  114. Algeciras-Schimnich A, Shen L, Barnhart BC, Murmann AE, Burkhardt JK, Peter ME. Molecular ordering of the initial signaling events of CD95. Mol Cell Biol. 2002 Jan; 22(1):207-20.
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  115. Vlahakis SR, Algeciras-Schimnich A, Bou G, Heppelmann CJ, Villasis-Keever A, Collman RG, Paya CV. Chemokine-receptor activation by env determines the mechanism of death in HIV-infected and uninfected T lymphocytes. J Clin Invest. 2001 Jan; 107 (2):207-15
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  116. Dockrell DH, Badley AD, Algeciras-Schimnich A, Simpson M, Schut R, Lynch DH, Paya CV. Activation-induced CD4+ T cell death in HIV-positive individuals correlates with Fas susceptibility, CD4+ T cell count, and HIV plasma viral copy number. AIDS Res Hum Retroviruses. 1999 Nov 20; 15 (17):1509-18
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  117. Trushin SA, Pennington KN, Algeciras-Schimnich A, Paya CV. Protein kinase C and calcineurin synergize to activate IkappaB kinase and NF-kappaB in T lymphocytes. J Biol Chem. 1999 Aug 13; 274 (33):22923-31
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  118. Algeciras-Schimnich A, Griffith TS, Lynch DH, Paya CV. Cell cycle-dependent regulation of FLIP levels and susceptibility to Fas-mediated apoptosis. J Immunol. 1999 May 1; 162 (9):5205-11
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  119. Badley AD, Dockrell DH, Algeciras A, Ziesmer S, Landay A, Lederman MM, Connick E, Kessler H, Kuritzkes D, Lynch DH, Roche P, Yagita H, Paya CV. In vivo analysis of Fas/FasL interactions in HIV-infected patients. J Clin Invest. 1998 Jul 1; 102 (1):79-87
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  120. Dockrell DH, Badley AD, Villacian JS, Heppelmann CJ, Algeciras A, Ziesmer S, Yagita H, Lynch DH, Roche PC, Leibson PJ, Paya CV. The expression of Fas Ligand by macrophages and its upregulation by human immunodeficiency virus infection. J Clin Invest. 1998 Jun 1; 101 (11):2394-405
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  121. Algeciras A, Dockrell DH, Lynch DH, Paya CV. CD4 regulates susceptibility to Fas ligand- and tumor necrosis factor-mediated apoptosis. J Exp Med. 1998 Mar 2; 187 (5):711-20
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  122. Holtz-Heppelmann CJ, Algeciras A, Badley AD, Paya CV. Transcriptional regulation of the human FasL promoter-enhancer region. J Biol Chem. 1998 Feb 20; 273 (8):4416-23
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  123. Folgueira L, Algeciras A, MacMorran WS, Bren GD, Paya CV. The Ras-Raf pathway is activated in human immunodeficiency virus-infected monocytes and particpates in the activation of NF-kappa B. J Virol. 1996 Apr; 70 (4):2332-8
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