Ian T. Mark, M.D., MSM

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SUMMARY

The research of Ian T. Mark, M.D., MSM, focuses on advanced imaging techniques to study diseases involving the brain, head and neck, and spine. As a neuroradiologist, he focuses on challenging situations where locating the cause of symptoms is difficult to solve with typical imaging techniques. He translates new neuroimaging solutions to direct patient care. He aims to improve patient outcomes by focusing on disease sources and specifically targeting affected areas to better guide treatment.

Focus areas

• Pituitary tumors. Successful outcomes in patients with Cushing disease are tied directly to the ability to accurately identify and localize small pituitary tumors. Dr. Mark uses several new imaging techniques, including advanced MRI, ultrasound and photon-counting CT, to find small pituitary tumors that are difficult to see with conventional imaging methods.
• Spontaneous intracranial hypotension. Spontaneous cerebrospinal fluid (CSF) leaks can cause debilitating symptoms for patients and can be challenging to interpret on MRI and CT scans. Dr. Mark explores techniques to diagnose CSF leaks and to expand the understanding of their underlying pathophysiology.

These include:

• Dynamic radiography of the spinal cord, called myelography.
• Serum and CSF biomarkers.
• Brain viscoelastography with MRE.

Significance to patient care

By studying spontaneous intracranial hypotension and pituitary tumors, Dr. Mark aims to create new techniques to show areas of treatable pathology. Such areas are often difficult to see using current testing technology. By finding the patients with treatable conditions early on, Dr. Mark hopes to improve outcomes.

Professional highlights

• ARRS Scholarship, American Roentgen Ray Society, 2024-2026.
• Hanafee Grant, American Society of Head & Neck Radiology, 2023-2024.
• ASSR Research Grant, American Society of Spine Radiology, 2023-2024.
• Scholar Award in Neuroradiology Research, American Society of Neuroradiology, 2021-2023.