Mitchell R. Humphreys, M.D.

Location

SUMMARY

Dr. Humphreys' research interests include urological malignancies and benign diseases, as well as innovative, minimally invasive surgical procedures and technology to improve treatments and outcomes. He also participates in international and multi-institution consortiums to answer some of the biggest questions facing urology and patients.

Specific research interests include:

• Health disparities.
• Prostate cancer.
• Cost-effectiveness analysis.
• Benign prostatic hyperplasia (BPH).
• Nephrolithiasis.
• Upper tract urothelial carcinoma.
• Image-guided surgery.
• Patient outcomes.

Focus areas

• Endourology Disease Group for Excellence (EDGE) Research Consortium
  • International multi-institution group of investigators.
  • Randomized trial comparing holmium laser to thulium fiber laser for stone lithotripsy.
  • Randomized trial comparing ureteral stent length at three versus seven days following ureteroscopy.
  • Microbiome of patients with diabetes who have kidney stones.
  • The impact of recurrent urinary tract infections and kidney stones.
• Benign prostatic hyperplasia
  • Early apical release during holmium laser enucleation of the prostate (HoLEP).
  • Patient quality-of-life outcomes following BPH surgery.
  • Evaluating large-language models for artificial intelligence in BPH.
  • Outcomes of HoLEP in patients with metabolic syndrome.
  • Blue Halo urinary stent for bladder outlet obstruction in males.
• Oncology
  • The impact of patient decision aids on surgical outcomes in patients with prostate cancer.
  • Development of minority-specific decision aids for patients with prostate cancer.
  • Impact of prostate cancer screening in the community setting for minority populations.
  • MitoGel for upper tract urothelial carcinoma — prospective registry.
  • MRI and prostate imaging — the ability to predict biopsy results and surgical outcomes.
• Endourology
  • Uriprene dissolvable ureteral stent following ureteroscopy and laser lithotripsy.
  • Robot-assisted percutaneous access for upper tract kidney stone treatment.
  • Association between reimbursement and patient complexity for kidney stone treatment.
  • Association between fluoroscopy and offspring: a study of occupational exposure on family planning.

Significance to patient care

Dr. Humphreys' research covers the entire spectrum of urological disease, including:

• Looking at individual cells that can influence the way certain diseases present and cause symptoms.
• Studying the impact of disease on a patient's quality of life, including financial implications.
• Discovering new and innovative ways to treat diseases.
• Recognizing the potential for disease before it causes major symptoms.

Dr. Humphreys collaborates with others. He also uses large datasets and the capabilities of computer learning and artificial intelligence. This translates to new discoveries for patients that lessen the impact of disease and offer new cures and new hope.

Professional highlights

• Editor, Frontiers in Medicine, 2017-present.
• President, GSD Healthcare Inc., 2013-present.
• Founding member, Endourology Disease Group for Excellence, 2011-present.
• Urology Educator of the Year, Mayo Clinic College of Medicine and Science, 2015.
• Outstanding Young Physician Award, University of Missouri School of Medicine, 2012.