Faculty

SangKon Oh, Ph.D.

Clinical Studies

Immune Phenotypes of Recurrent Respiratory Papillomatosis (RRP) Patients Scottsdale/Phoenix, Ariz.
The purpose of this study is to develop a novel immunotherapeutic strategy to treat Recurrent Respiratory Papillomatosis (RRP) patients and cure the disease.
Study of Immune Tolerance Mechanisms in Kidney Transplant Patients Scottsdale/Phoenix, Ariz.
Hypothesis: we hypothesize that the abundance and functions of Breg subsets in kidney transplant patients could be associated with transplant tolerance and rejection, including DSA-mediated kidney transplant rejection. In addition, oral corticosteroid treatment significantly alters the frequency and function of Breg subsets, which could lead altered clinical outcomes.

Aims, purpose, or objectives:
1. Investigate the frequency Bregs and their ability to express IL-10 along with other immune cells in the context of tolerance/rejection in kidney transplant patients.
we hypothesize that the abundance and functions of Breg subsets in kidney transplant patients could be associated with transplant tolerance and rejection, including DSA-mediated kidney transplant rejection.

2.Investigate the frequency and functions of Bregs along with other immune cells in the setting of long term corticosteroid use.
We hypothesize that oral corticosteroid treatment significantly alters the frequency and function of Breg subsets, which could lead altered clinical outcomes.

Alloimmune T-Cell Responses in Highly Sensitized Kidney Transplant Recipients: A Pilot Study Rochester, Minn., Scottsdale/Phoenix, Ariz.
The purpose of this study is to better understand how the immune system reacts to kidney transplantation in individuals who are potentially at higher risk for rejection.
OX40L As a Functional Biomarker for Liver Fibrosis Scottsdale/Phoenix, Ariz.
The primary purpose of this study is to investigate whether the abundance of OX40L expression is associated with the development of hepatic fibrosis.