Oana M. Dumitrascu, M.D.

The primary objectives of this study are to determine whether treatment of OSA with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and improves stroke outcomes at 3 months in patients who experienced an ischemic stroke.

This study aims to provide clinical validation of EyeQuant, a fully automated retinal image analysis system for computation of vascular biomarkers indicative of cognitive disorders, using retinal fundus photographs collected from patients with mild cognitive impairment, Alzheimer’s disease, and vascular dementia. When deployed and commercialized, this system can assist in the identification of these biomarkers to aid in assessing drug/treatment efficacy and screening of the aging population in primary care practices and thus enable the early detection and effective management of patients with neurodegenerative disorders.

This study aims to create a repository of retinal images that can be used to develop ocular biomarkers for various neurological conditions.