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Clinical Studies

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  • Clinical Evaluation of a PET/MR System Rochester, Minn.

    The first objective of this pilot research protocol is to evaluate the quality of PET from the SIGNA PET/MR system and to compare the quantitative accuracy of PET images from the PET/MR system to PET images from a standard PET/CT system. The second objective of this pilot research protocol is to compare the image quality from MRI images acquired on the SIGNA PET/MR to clinical MR images acquired on a standard 3.0T MRI system.
  • Improving PET Image Quality and Quantification by Using Motion Correction, Parametric Imaging and MAP Reconstruction Rochester, Minn.


    The aims of this research project are to assess the effectiveness of motion correction software for patients undergoing PET brain scans, to assess the data acquisition and image processing workflow for parametric analysis of brain and whole body scans, and to assess the quality of PET images reconstructed with maximum a posteriori (MAP) reconstruction algorithm.

Closed for Enrollment

  • Clinical Evaluation of a Transmit/Receive Head Coil for PET/MR Brain Studies Rochester, Minn.

    The purpose of this study is to evaluate an attenuation map for a transmit/receive (T/R) head coil used on the GE SIGNA PET/MR system. An attenuation map of the T/R head coil will be developed and evaluated in phantom experiments followed by the patient studies. The repeatability of generating patient-specific attenuation maps from Zero Echo Time (ZTE) MR images acquired with the T/R head coil will also be assessed.
  • Clinical Evaluation Of MP26 Features in Adults Rochester, Minn.

    The purpose of the study is to collect representative clinical images (head and whole-body scans) of demonstrated diagnostic quality using the next-generation SIGNA PET/MR device equipped with investigational software components in adult population. The images and summary data from this study are intended for use in regulatory submission.
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