Clinical Trials

The overall goal of this research is to identify patients in clinical practice that have unrecognized hypophosphatasia (HPP) and select appropriate candidates for therapy. The purpose of this proposal is to identify the prevalence of adults with hypophosphatasia within a previously identified fibromyalgia cohort at our institution.

DS 5565 will be better than placebo (sugar pill without active drug) in managing fibromyalgia pain and will be well tolerated.

The purpose of this study is to evaluate the utilization of the sleep pulse oximeter test for fibromyalgia patients based on the Berlin and STOP-BANG survey results. The aim is to enhance individualized medicine testing for fibromyalgia patients.

The purpose of this study is to examine the current and (potential) future therapeutic relevance of PGx testing for a group of patients with fibromyalgia in order to improve patient clinical care at Mayo Clinic with more effective and efficient prescribing of medications.

In this pilot study we propose to gather preliminary data on whether transdermal magnesium chloride can improve quality of life in patients with fibromyalgia. Forty women with fibromyalgia will be enrolled in this study. Participants will be asked to apply a topical solution of magnesium chloride on their extremities 3 times daily for 28 consecutive days. Three questionnaires measuring quality of life will be administered at baseline, at 2 weeks, and at 4 weeks (end of study).

The purpose of the study is to describe the experience of men diagnosed with fibromyalgia living in the United States. Specifically, this study will take into account the experiences of fibromyalgia within men, an underrepresented gender group in fibromyalgia research and treatment.

The purpose of this study is to build the knowledge of in-situ clinical experiences essential to developing decision aids for patients considering treatment options for fibromyalgia. Using ethnographic study design, we aim to understand how patients and clinicians think, talk, and feel about treatment options for fibromyalgia by directly observing clinical encounters.

The primary purpose of this study is to assess the rate of utilization of Autonomous Sensory Meridian Response (ASMR) in our cohort of patients with fibromyalgia (FM).

The purpose of this study is to evaluate the experiences and short term effects of the Eight Brocades (EB) for patients with fibromyalgia (FM).

The purpose of this study is to study the feasibility of a wearable brain sensing wellness device to provide mindfulness training to fibromyalgia patients.

In this study the investigators hypothesize that the presence of a Mayo Clinic certified therapy dog will provide additional benefits to patients suffering from fibromyalgia currently enrolled in the Mayo Clinic Fibromyalgia Program.

The purpose of this study is to gather preliminary data on feasibility and effectiveness of cognitive behavior therapy (SHUT-I) versus traditional sleep hygiene education on insomnia in patients with fibromyalgia.

The primary purpose for this study is to assess if any relationship exists between participation in the Fibromyalgia and Chronic Fatigue Clinic (FCFC) class (12 hours or 8 hours educational session/class) and overall reduction in symptom severity and/or increased level of functioning, in our fibromyalgia patients.

The purpose of this study is to gather preliminary data on the effectiveness and feasibility of the Amygdala Retraining Program, a mind-body practice, on fatigue, quality of life and sleep in patients with Chronic Fatigue Syndrome, Chronic Fatigue, and Fibromyalgia.