In Situ Remote Monitoring in Older Patients at Risk of Stroke

Overview

About this study

The purpose of this study is to examine the relationship between stroke risk stratification categories, according to ABCD2 scoring and post-ischemic stroke status, and passively- and actively collected data (from a smartphone application). Also, to investigate patterns of changes in behavioral and physiological states associated with a stroke event. Addtionally, to explore whether digital phenotyping can provide a valid, useful method for tracking behavioral and physiological changes over time. If our proposed protocol is validated, it has the potential to be applied in both clinical and research settings to improve stroke screening for older adults

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Men and women between the ages of 18 and 100.
Must present with TIA or IS symptoms and be classified as at risk of stroke using the ABCD2 scoring methodology OR be already recently diagnosed with IS (permanent ischemic lesion).
Able to use a smartphone.
Report at least moderate smartphone use.

Exclusion Criteria:

Aged < 18 and > 100 at time of enrollment.
Heart rate monitoring medications.
History of insomnia.
History of panic disorder.
History of severe anxiety.
History of severe depression.
BMI > 35.
Past or current substance use disorder.
Urinary incontinence.
Alzheimer’s disease.
Borderline personality disorder.
Antisocial personality disorder.
Dementia.
Pre-existing brain and/or cognitive disorder.
Cane/walker/wheelchair use:
- Unstable or acute medical conditions.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 11/7/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Bradley Erickson, M.D., Ph.D.	Open for enrollment	Contact information: Stephanie Zawada (480) 301-8000 Zawada.Stephanie@mayo.edu
Jacksonville, Fla. Mayo Clinic principal investigator Benjamin Pollock, Ph.D., M.S.	Open for enrollment	Contact information: Stephanie Zawada (480) 301-8000 Zawada.Stephanie@mayo.edu
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Bart Demaerschalk, M.D.	Open for enrollment	Contact information: Stephanie Zawada (480) 301-8000 Zawada.Stephanie@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Bradley Erickson, M.D., Ph.D.

Open for enrollment

Contact information:

Stephanie Zawada

(480) 301-8000

Zawada.Stephanie@mayo.edu

Jacksonville, Fla.

Mayo Clinic principal investigator

Benjamin Pollock, Ph.D., M.S.

Open for enrollment

Contact information:

Stephanie Zawada

(480) 301-8000

Zawada.Stephanie@mayo.edu

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Bart Demaerschalk, M.D.

Open for enrollment

Contact information:

Stephanie Zawada

(480) 301-8000

Zawada.Stephanie@mayo.edu

More information

Publications

Publications are currently not available

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