Evaluating the Ability of An AI Algorithm to Determine Liver/Spleen Volumes

Overview

About this study

The purpose of this study is to evaluate an artificial intelligence (AI) algorithm for generation of liver and spleen volumes from abdominal CT exams, performed with intravenous contrast unless contraindicated, as part of clinically indicated examinations. The clinical indications include chemotherapy, chronic liver disease, focal liver lesions and undergoing surgical liver resections or minimally invasive procedures involving the liver and spleen. AI algorithm will be used to measure liver and spleen volumes after the clinical CT exam is done to test whether reading radiologists will accept these AI-generated measures, populate them into their report. In addition, the study will assess feedback from reading radiologists. We will quantify their acceptance and/or rejection to determine if our software can be validated in a prospective study.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Individuals ≥ 18 years of age.
Patients: Routine abdominal CT imaging ordered.
Physicians: members of Mayo Clinic’s radiology, gastroenterology, hepatology, and oncology department across the enterprise.
Participants must agree to consent statement.

Exclusion Criteria:

Individuals < 18 years of age.
Patients: Suboptimal quality CT acquisition (noise, motion, etc.).
Physicians: None.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 10/24/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Sudhakar Venkatesh, M.D.	Closed-enrolling by invitation What is this? (?) "Close" Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.	Contact information: Stephanie Kiper Kiper.Stephanie@mayo.edu
Jacksonville, Fla. Mayo Clinic principal investigator Frank Chen, M.D.	Closed-enrolling by invitation What is this? (?) "Close" Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.	Contact information: Stephanie Kiper Kiper.Stephanie@mayo.edu
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Motoyo Yano, M.D., Ph.D.	Closed-enrolling by invitation What is this? (?) "Close" Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.	Contact information: Stephanie Kiper Kiper.Stephanie@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Sudhakar Venkatesh, M.D.

Closed-enrolling by invitation

Contact information:

Stephanie Kiper

Kiper.Stephanie@mayo.edu

Jacksonville, Fla.

Mayo Clinic principal investigator

Frank Chen, M.D.

Closed-enrolling by invitation

Contact information:

Stephanie Kiper

Kiper.Stephanie@mayo.edu

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Motoyo Yano, M.D., Ph.D.

Closed-enrolling by invitation

Contact information:

Stephanie Kiper

Kiper.Stephanie@mayo.edu

More information

Publications

Publications are currently not available

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