Clinical Trials

Overview

About this study

The purpose of this study is to obtain sufficient fresh kidney tissue from patients with history of kidney stones or without a history of kidney stones to perform assay transposase accessible chromatin (ATAC), cellular indexing of transcriptomes and epitomes (CITE), and RNA expression and protein (REAP) sequencing studies on fresh, snap frozen versus paraffin embedded samples.  Differential expression of renal interstitial cells, genes and encoded proteins will be confirmed by flow cytometry, qPCR, and immunofluorescence/immunohistochemistry respectively.  In addition, random urine and plasma/serum will be biobanked for biomarker studies to correlate with findings in the kidney tissue.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Participating Mayo Clinic locations

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