Influence of Exercise on Corticospinal Tract Connectivity

Overview

About this study

The purpose of this study is to use neurological techniques to obtain quantitative measurements of nervous system control of skeletal muscle activity in adults aged 18-80 who are either long-term resistance exercisers or who are untrained.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Participant must have a BMI between 18.5 and 40.
  • Participant be aged between 18 and 80.
  • Participant must use the Mayo Clinic patient online portal.
  • Participant must be able to understand English without the need of an interpreter.
  • Must be willing to be contacted for research.
  • Participant must be willing and capable to provide consent.
  • Participants shall be generally healthy as deemed acceptable by the principal investigator.
  • Men and women will be participant in this study. Women cannot be pregnant during this study.

Exclusion Criteria:

  • Gastric surgery, pacemaker placement, weight loss surgery, metabolic and obstetric surgery.
  • Smokers will be excluded from the study.
  • Insulins, common diabetic drugs, anti-hyperglycemic drugs, beta blockers cardiac selective, beta-blockers noncardiac selective, oral steroids, opioids anti-depressants, and hormones.
  • Disorder of coronary artery, hepatic failure, gastroparesis, disorder of the adrenal gland, drug related disorders, substance abuse, malignant neoplastic disease, psychotic disorders, disorder of skeletal muscle, finding of brain, chronic kidney disease, renal failure syndrome, disorder of pulmonary circulation, cerebrovascular disease, neuro developmental disorder, disorder of immune function, disorder of central nervous system.
  • Participants are not to have an abnormal value as part of a lipid panel within the past 6 months.
  • Participant will be excluded if they have recreational drug use or a history of alcohol abuse.
  • Inability or unwillingness of individual or legal guardian/representative to give written informed consent.
  • Current or past participation within a specified timeframe in another clinical trial, as warranted by the administration of this intervention.
  • Participant will be excluded if they have epilepsy.
  • Participant will be excluded if they have cranial metal/device implants.
  • Participant will be excluded if they are pregnant.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 10/4/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

K Nair, M.D., Ph.D.

Open for enrollment

Contact information:

Katherine Klaus

(507) 255-6770

Klaus.Katherine@mayo.edu

More information

Publications

Publications are currently not available
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CLS-20555051

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