Clinical Trials

Overview

About this study

Hypothesis:  Hair cortisol and cortisone in patients with Cushing syndrome (CS) will be elevated compared to patients with Pseudo-Cushing syndrome and healthy volunteers as established by Mayo Medical Laboratories.

Aims:

1. To establish optimal cut-off value of scalp hair cortisol and cortisone measured by novel Liquid-Chromatography tandem mass spectrometry (LC-MS/MS) assay developed by Mayo Medical laboratories

in patients with endogenous CS and in patients in whom CS was suspected but diagnosis rejected. 

2. To compare performance of scalp hair cortisol and cortisone based on mild, moderate or severe clinical suspicion of CS and currently available laboratory tests including 24-h urinary cortisol and LNSC.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Participating Mayo Clinic locations

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