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A Study Biomarkers for Diagnosis, Disease Activity, Prediction of Response to Therapy and Prognosis in Spondyloarthritis

Overview

About this study

The purpose of this study is to establish a biorepository of biosamples from patients with spondyloarthritis (SpA). This biorepository will enable future investigation of biomarkers associated with SpA based on new understanding of the human genome, epigenome and microbiome.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adult patients ≥ 18 years of age.
  • Must be able to provide informed consent.
  • Physician diagnosis of axSpA, peripheral SpA or inflammatory bowel disease related arthritis.

Exclusion Criteria:

  • Individuals who do not comprehend English (i.e., participants must be able to read and sign a consent form without the assistance of an interpreter).
  • Individuals who are unable to sign consent (e.g., mentally challenged, those declared legally incompetent).
  • Individuals regarded as belonging to a vulnerable population (e.g., prisoners).
  • Antibiotic exposure within two weeks of stool microbiome collection.
  • Patients who have a history of malignancy, exception: documented history of cured non-metastatic squamous or basal cell skin carcinoma will be allowed.

Eligibility last updated 4/5/23. Questions regarding updates should be directed to the study team contact.

 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Kerry Wright, M.B.B.S.

Open for enrollment

Contact information:

Patricia Kennedy

(507) 266-1986

Kennedy.Patricia1@mayo.edu

More information

Publications

Publications are currently not available

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CLS-20552363

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