Clinical Trials

Overview

About this study

Hypothesis: Novel MRI pulse sequences developed at AMRIT for high resolution functional imaging will provide greater sensitivity for activation detection and less susceptibility to effects of neurovascular uncoupling than standard BOLD fMRI pulse sequences

Objectives:

1. To compare high resolution advanced MRI pulse sequences for functional imaging (functional VASO, ASL) to conventional BOLD fMRI pulse sequence for assessment of sensitivity for detection of language cortical activation at 3T
2. 1) To compare high resolution advanced MRI pulse sequences for functional imaging (functional VASO, ASL) to conventional BOLD fMRI pulse sequence for assessment of sensitivity for detection of language cortical activation at 7T
3. To determine whether such novel MRI pulse sequences will be less susceptible to the effects of neurovascular uncoupling and thus capable of providing more reliable activation maps in the setting of brain tumors and other resectable brain lesions

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Participating Mayo Clinic locations

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