Clinical Trials

Inclusion Criteria:

Multiple Sclerosis

• Diagnosed with multiple sclerosis according to the 2017 revised McDonald criteria.
• Age ≥18 years.

 Physician determined disease progression

• Patient must be able to walk without a walker for the motion tests (e.g. 25 ft walk)
• Patient must be enrolled in IRB#08-007846 and actively participating in sample collections.
• Patient must agree to the lumbar puncture and skin biopsy components of IRB#08-007846.

Progressive Immune-Mediated Neurodegenerative Disorder

• Age ≥ 18 years.
• Physician determined disease progression
• Gait disorder is primarily associated with a seropositive autoimmune CNS disorder.
• Patient must be able to walk without a walker for the motion tests (e.g. 25 ft walk).
• Patient must be enrolled in IRB#08-007846 and actively participating in sample collections.
• Patient must agree to the lumbar puncture and skin biopsy components of IRB#08-007846.

Exclusion Criteria: 

Multiple Sclerosis

• Unable to have annual clinical MRI.

Progressive Immune-Mediated Neurodegenerative Disorder

• Unable to have annual clinical MRI.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 11/22/23. Questions regarding updates should be directed to the study team contact.