The Impact of a Geriatric Assessment in Elderly Patients with Multiple Myeloma

Overview

About this study

The purpose of this study is to evaluate the association between a baseline comprehensive geriatric assessment (cGA) and chemotherapy toxicity in the first 4 months of treatment measured by treatment-related adverse events, patient-reported outcomes (PROs), and treatment discontinuation in older patients (≥ 65 years) with multiple myeloma (MM).

Multiple myeloma (MM) is a blood cancer that affects a type of white cell called plasma cell. It mainly affects older individuals and has an average age at diagnosis of 69 years.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Age ≥ 65 years.
Diagnosis of MM based on IMWG diagnostic criteria 64.
Newly diagnosed or have received 1 prior line of treatment.
Planned to start a new treatment for MM within 30 days.
Transplant eligible or ineligible.
Fluent in English (all assessment tools are in English).
Able to provide written informed consent.

Exclusion Criteria:

Received > 1 prior line of treatment.
Patients included in an interventional therapeutic trial.
Not able to give informed consent.
Severe mental or cognitive disorder precluding geriatric assessment.

Eligibility last updated 1/20/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Shaji Kumar, M.D.	Open for enrollment	Contact information: Shaji Kumar M.D. (507) 284-5096 Kumar.Shaji@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Shaji Kumar, M.D.

Open for enrollment

Contact information:

Shaji Kumar M.D.

(507) 284-5096

Kumar.Shaji@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials