A Study of Migraine Attack Prediction for Improved Patient Outcomes

Overview

About this study

The purpose of this study is to create individualized prediction models utilizing sensor data and cognitive function which will accurately identify the premonitory phase of the migraine attack and predict an oncoming migraine headache.

This study will seek to determine which measures differ between migraine attack phases (e.g., interictal vs. premonitory), develop an initial migraine prediction algorithm, and to provide insights into how long prior to headache onset premonitory changes begin. It will also look for migraine phenotypes associated with changes in sensor-measured data during the preictal vs. ictal or interictal periods.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Ages 21-70.
Migraine with or without aura.
2+ migraine attacks per month, 2-14 migraine days per month and 2-20 headache days per month.
Stable headache pattern over the previous 3 months as reported by the study participant.
Own an Apple or Android mobile device or personal computer to host headache diary.

Exclusion Criteria:

Unwilling or unable to complete the study assessments.
Conditions or medications that in the investigators’ opinion may alter the collected sensor signals (e.g., conditions affecting the heart such as arrythmia).
Other headache disorders, secondary headaches, migraine thought to be caused by trauma, infection, ischemic stroke.
Current pregnancy or lactation.
Hemiplegic migraine, migraine with brainstem aura.
Aura of any type with > 50% of migraine attacks.

Eligibility last updated 7/1/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Gina Dumkrieger, Ph.D., M.S.	Closed for enrollment	Contact information: Dakota Hohenwalter (480) 342-3775 Hohenwalter.Dakota@mayo.edu

Mayo Clinic Location

Status

Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Gina Dumkrieger, Ph.D., M.S.

Closed for enrollment

Contact information:

Dakota Hohenwalter

(480) 342-3775

Hohenwalter.Dakota@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials